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Synthetic Chemistry PhD Projects, Programs & Scholarships in the UK

We have 90 Synthetic Chemistry PhD Projects, Programs & Scholarships in the UK

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  Chemo-enzymatic Synthesis and Potential Applications of Novel Heterocyclic Alkaloids
  Dr H Deng, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  Developing an enzymatic toolbox to make complex modified peptides
  Prof M Jaspars, Dr W Houssen, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

The pharmaceutical industry has identified a major gap in its portfolio. On the one hand, they are excellent at discovering small molecules that act via a lock and key type mechanism.
  Genome mining of novel antimicrobial natural products from new bacterial strains
  Dr H Deng, Prof M Jaspars
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  The synthesis and photolysis of photoacid generators used in polymer resists for making silicon chips
  Dr M J Plater, Dr W T A Harrison
Applications accepted all year round

Funding Type

PhD Type

Polymer resists are used as thin films in the manufacture of silicon chips. They are spin coated onto a silicon wafer and irradiated through a pattern in a mask.
  Development of cutting-edge microporous adsorbents for gas separation processes
  Dr C Fernandez-Martin, Dr A Majumder
Applications accepted all year round

Funding Type

PhD Type

Developing cost-effective adsorbents aiming at separating impurities from different gas mixtures is a real and necessary challenge for the industry, especially the energy sector.
  Asymmetric catalysis using environmentally benign calcium complexes
  Dr B Ward
Applications accepted all year round

Funding Type

PhD Type

Dr Ben Ward http://www.cardiff.ac.uk/people/view/38527-ward-benjamin is looking for a PhD student to work on the research project ’Asymmetric catalysis using environmentally benign calcium complexes’.
  Computation-led materials design for heterogeneous catalytic applications
  Dr A Logsdail
Applications accepted all year round

Funding Type

PhD Type

Computation-led materials design for heterogeneous catalytic applications. PhD Supervisor. Dr. Andrew J. Logsdail http://www.cardiff.ac.uk/people/view/481607-logsdail-andrew.
  Investigating the use of photoactive crystalline porous materials such as metal-organic frameworks (MOFs) as a platform for nanofluidic devices
  Dr T Easun
Applications accepted all year round

Funding Type

PhD Type

Dr Timothy Easun http://www.cardiff.ac.uk/people/view/69904-easun-tim is looking for a PhD student to work on the research project ’Metal-Organic Frameworks and Supramolecular Photochemistry’.
  The Productive Merger of the Borrowing Hydrogen Principle with Organocatalysis
  Dr L Morrill
Applications accepted all year round

Funding Type

PhD Type

Applications are invited for self-funded students wishing to perform research towards a Ph.D. in synthetic organic chemistry under the supervision of Dr Louis C.
  Development of novel nanostructures for the next generation of Fuel Cell vehicles
  Dr E Gkanas
Application Deadline: 8 November 2019

Funding Type

PhD Type

For hydrogen storage applications, Metal Organic Frameworks (MOFs) have been tested due to their high porosity and large surface area (can be used to trap hydrogen molecules).
  Smart sniffer device for detection of illicit substances
  Dr E Dossi
Application Deadline: 1 November 2019

Funding Type

PhD Type

The project is of high international relevance due to need to fight organised crime as well as supporting and facilitating the activities of security practitioners at national and EU level and aligns with the CDS strategic priorities.
  Antibody-drug conjugates (ADCs) for the treatment of solid tumours
  Dr S Karagiannis, Prof J Downward
Application Deadline: 29 November 2019

Funding Type

PhD Type

An Antibody-Drug Conjugate (ADC) comprises an antibody targeted toward a tumour cell surface antigen, coupled through a chemical linker to a highly-cytotoxic drug.
  Chemically editable 3D tumour microenvironments to explore and exploit tumour immunity
  Dr O Pearce, Dr B Schumann
Application Deadline: 29 November 2019

Funding Type

PhD Type

Immunotherapy of cancers may offer progression free survival that is not seen with conventional chemotherapies. However, immunological barriers present within the tumour reduce response rates to therapy.
  EPSRC Centre for Doctoral Training in Soft Matter for Formulation and Industrial Innovation (SOFI2 CDT)

Funding Type

PhD Type

16 fully funded, four-year PhD studentships are available in the EPSRC Centre for Doctoral Training in Soft Matter for Formulation and Industrial Innovation (SOFI2 CDT) commencing in September 2019, for graduates in the physical and biological sciences, mathematics and engineering.
  In silico approaches to enable optimisation of small molecule binding by perturbing and interacting with water networks.
  Dr S Hoelder, Dr M Meniconi
Application Deadline: 17 November 2019

Funding Type

PhD Type

The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes. We are committed to attracting and developing the best minds in the world to join us in our mission—to make the discoveries that defeat cancer.
  Effect of Induced Plasticity on the Very High Cycle Fatigue of aluminium alloy under biaxial stress field
  Dr M Grasso, Dr H Hadavinia
Applications accepted all year round

Funding Type

PhD Type

One of the most important task in the design process is the assessment of cyclic loading since half of the mechanical failures are due to fatigue.
  Mechanical Properties of Interfaces in 3D Printed Single- and Multi-Material Parts
  Dr M Grasso, Dr H Hadavinia
Applications accepted all year round

Funding Type

PhD Type

Additive Manufacturing techniques can be seen as an important change in the manufacturing methodology as the final form is achieved through a bottom-up approach, via the addition of material in a layer-by-layer fashion.
  Synthesis and Anti-Cancer Evaluation of New Heterocyclic Quinones
  Prof F Aldabbagh, Dr N Hill
Applications accepted all year round

Funding Type

PhD Type

The group has published on small molecules with specificity towards hypoxic cells associated with solid tumours, reductase enzymes over-expressed in cancer, as well as, aziridines that induce hypersensitivity from Fanconi anaemia cells and those carrying mutations in the BRCA (Breast Cancer Susceptibility) genes.
  Synthesis of a toolbox of bioisosteric building blocks for drug discovery
  Dr S Wren
Applications accepted all year round

Funding Type

PhD Type

This project involves the preparation of important building blocks that feature bioisosteres (for application in various medicinal chemistry contexts).
  Twisted Aromatic Molecules for Energy Applications
  Dr I Wright
Application Deadline: 1 February 2020

Funding Type

PhD Type

This interdisciplinary project will involve the synthesis of twisted polyaromatic hydrocarbons with functionality suitable for organic solar cells and energy storage applications.
  Activating Carbon Dioxide Utilising Atmospheric Pressure Gas Plasma
  Dr B Buckley, Dr F Iza
Application Deadline: 31 July 2020

Funding Type

PhD Type

This project will be part of the Doctoral Training Centre on Plasma interactions with Liquids. The Buckley group has embarked on a programme of research directed at carbon dioxide utilisation (CDU) and has reported initial efforts in the area.
  Activation of Carbon Dioxide to the synthesis of Biologically Relevant Molecules
  Dr B Buckley
Application Deadline: 31 July 2020

Funding Type

PhD Type

This project will look at the selective modification of compounds to deliver new/non-natural amino acids/peptides. The approach will use a new carboxylation process developed in our group.
  Novel Cyclic Peptides for Biomedical Imaging and Therapeutic Targeting
  Prof M Zanda
Applications accepted all year round

Funding Type

PhD Type

Cyclic Peptides have a wide range of applications as drugs and diagnostics, and have often higher receptor affinity, metabolic stability and better pharmacokinetic properties compared to their linear counterparts, but their synthesis still presents significant challenges.
  Novel synthetic approaches to antimicrobial natural products and investigations of their bioactivity
  Prof A Malkov
Applications accepted all year round

Funding Type

PhD Type

The aim of the project is to develop new highly effective anti-tubercular agents. Previously, it has been established that terpenes isolated from marine organisms possess a number of important antibacterial properties.
  Rapid Synthesis of Fluorinated Drug Scaffolds
  Dr G Weaver
Applications accepted all year round

Funding Type

PhD Type

This project will involve the synthesis and characterisation of new heterocyclic compounds which can act as core scaffolds for drug development.
  Redox Flow Battery Materials for Energy Storage
  Dr P Nockemann
Applications accepted all year round

Funding Type

PhD Type

INTRODUCTION. Applications from students (only UK/EU nationals due to funding restrictions) are invited for a research studentship at the School of Chemistry and Chemical Engineering at Queen’s University of Belfast.
  Chemical biology approaches to study the ubiquitin system
  Dr K Rittinger
Application Deadline: 12 November 2019

Funding Type

PhD Type

This 4-year PhD studentship is offered in Dr Katrin Rittinger’s Group based at the Francis Crick Institute (the Crick).
  Design, Synthesis and Biological Evaluation of novel inhibitors of the JAK-STAT signalling pathway with potential application as immune oncology agents
  Dr R Whitehead, Dr K Finegan, Prof N Turner
Applications accepted all year round

Funding Type

PhD Type

Small molecule inhibitors of the JAK-STAT signalling pathway often possess interesting biological properties with many displaying potent anti-proliferative activity towards cancer cell lines.
  Molecular machines that “read” and “write”
  Dr S Webb
Applications accepted all year round

Funding Type

PhD Type

A key feature of biological systems is the storage and transmission of information, which maintains the complex chemical networks and functions within cells.
  Programmable Enzymatic Synthesis of Bioactive Compounds
  Prof S Flitsch, Prof P Barran
Applications accepted all year round

Funding Type

PhD Type

The aim of this project is to devise a conceptually novel and general platform that will deliver a step-change in complexity of de novo biosynthetic pathways by moving from manual to automated design, build and test.
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