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We have 49 Toxicology PhD Projects, Programmes & Scholarships for Self-funded Students in the UK

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Toxicology PhD Projects, Programmes & Scholarships for Self-funded Students in the UK

We have 49 Toxicology PhD Projects, Programmes & Scholarships for Self-funded Students in the UK

Inflammatory Arthritis in Childhood: Impact, Outcomes and Safety of Treatment

Juvenile Idiopathic Arthritis is the most common inflammatory arthritis of childhood. Although less common than arthritis in adults, a diagnosis of arthritis in a child can have lasting impacts on that child and their families through their entire lifespan. Read more

A 3D-Printed Blood-Brain-Barrier-on-a-Chip for Agrochemical Permeability Studies – CASE Studentship

The blood-brain barrier (BBB) tightly regulates the flow of material between the bloodstream and the brain. One of the big problems faced by a range of sectors, from pharmaceuticals to agrochemicals, is understanding how compounds interact with and cross this barrier. Read more

Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more

Therapeutic resolution of pulmonary arterial hypertension (PAH) by natural products

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Therapeutic resolution of coronavirus (COVID-19) diseases by natural products

  Research Group: Pharmacology and Experimental Therapeutics
Coronavirus now labelled as Covid-19 has become a global pandemic affecting around 200 countries. Currently neither any cure nor any vaccine for Covid-19 has been established. Read more

Polysialyltransferases as a target in metastatic cancer

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more

Identifying cognitive and biochemical changes underlying lifestyle risk factors for dementia

  Research Group: Pharmacology and Experimental Therapeutics
Dementia describes a group of age-associated conditions of which cognitive decline is a major feature. Alzheimer’s disease (AD) is the most common cause of dementia and is characterised by the onset of a gradual cognitive decline. Read more

Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer

  Research Group: Institute of Cancer Therapeutics
Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working. Read more

Development of Naked Mole Rat Colonic Crypt Models to Use in the Search for Bowel Disease Preventatives

  Research Group: Institute of Cancer Therapeutics
Diseases affecting the bowel such as colorectal cancer (CRC) and the inflammatory bowel diseases (IBD) ulcerative colitis and Crohn’s disease are major global healthcare challenges in the 21st century. Read more

Development of a personalized therapy for pulmonary arterial hypertension (PAH)

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

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