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University of Birmingham PhD Projects, Programs & Scholarships

We have 173 University of Birmingham PhD Projects, Programs & Scholarships

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Showing 61 to 90 of 173
  Development of native liquid extraction surface analysis mass spectrometry for drug discovery
  Prof H J Cooper
Applications accepted all year round

Funding Type

PhD Type

A fully-funded 4-year PhD studentship is available within the School of Biosciences at the University of Birmingham, in collaboration with AstraZeneca.
  Differential ion mobility spectrometry and mass spectrometry for proteomics
  Prof H J Cooper
Applications accepted all year round

Funding Type

PhD Type

Research in our laboratory focuses on the application of state-of-the-art mass spectrometry techniques to the global analysis of peptides and proteins.
  Elucidating the mechanisms of phospholipid transport in Gram-negative bacteria
  Research Group: BBSRC MIBTP
  Dr T Knowles
Applications accepted all year round

Funding Type

PhD Type

This project focuses on characterising the fundamental process of outer membrane lipid transport in Gram-negative bacteria, a largely unknown process which is only now being revealed.
  Elucidating the pathobiology of Candida albicans
  Dr R Hall
Applications accepted all year round

Funding Type

PhD Type

The Hall lab is interested in understanding the biology and virulence factors of fungal pathogens. Our research largely focuses on the opportunistic fungal pathogen Candida albicans, which causes a range of infections from superficial mucosal infections (i.e.
  Epitranscriptomic mechanisms in the maternal to zygotic transition of vertebrate embryos
  Dr M Soller, Prof F Mueller
Applications accepted all year round

Funding Type

PhD Type

Most mRNAs contain modified nucleotides in mRNA, but we know very little about their function (Haussmann et al, 2016, Dezi et al, 2016, Roignant and Soller, 2017).
  Eukaryotic gene expression: understanding the role of UPF1 in global mRNA processing and amyotrophic lateral sclerosis (ALS)
  Dr S Brogna
Applications accepted all year round

Funding Type

PhD Type

This project’s specific objective is to study the molecular role(s) that the RNA helicase UPF1 plays in RNA processing. UPF1 is a key player in nonsense-mediated mRNA decay (NMD), it is universally conserved in eukaryotes and is essential to the development of many organisms [1].
  From start to finish: roles for the N-end rule pathway of protein degradation in plant development and stress-response
  Research Group: BBSRC MIBTP
  Dr D Gibbs
Applications accepted all year round

Funding Type

PhD Type

In order to effectively co-ordinate their growth and development, plants need to be able to respond to changes in their environment, whether it is adapting to the seasons or coping with stresses.
  Genetic and molecular mechanisms of brain structural plasticity and neurodegeneration
  Research Group: BBSRC MIBTP
  Dr A Hidalgo
Applications accepted all year round

Funding Type

PhD Type

The project will test the potential of a molecular mechanism that we recently discovered, in modulating brain structural plasticity versus neurodegeneration.
  Genetic and molecular mechanisms of nervous regeneration and repair
  Dr A Hidalgo
Applications accepted all year round

Funding Type

PhD Type

The project will aim to discover novel molecular mechanisms that could promote central nervous system regeneration. The focus will be on how neurons and glia interact to match their cell populations and functions, and on the regenerative potential of glial cells.
  Integrated mathematical modelling and experimental research into interactions between microorganisms
  Dr J U Kreft
Applications accepted all year round

Funding Type

PhD Type

Our group aims to combine theoretical & experimental approaches to understand major problems in the ecology and evolution of microbes.
  Investigating the influence of polyploidy on the evolution of a major human fungal pathogen
  Dr E Ballou
Applications accepted all year round

Funding Type

PhD Type

The human fungal pathogen Cryptococcus neoformans undergoes an unusual morphological transition from haploid yeast to highly polyploid Titan cells during infection of the human host.
  Methods for quantitative genetic analyses in autotetraploids
  Prof Z Luo
Applications accepted all year round

Funding Type

PhD Type

Methods for quantitative genetic analysis have been well established in almost all important diploid plants and animal including humans, and have served as essential tools for dissecting the genetic architectures underlying agronomically, evolutionarily and medically interesting quantitative and complex traits.
  Molecular genetic characterization of Drosophila reproductive behaviours for exploitation in insect population control
  Research Group: BBSRC MIBTP
  Dr M Soller
Applications accepted all year round

Funding Type

PhD Type

Female reproductive behaviours in most insects profoundly change after mating leading to rejection of courting males and induction of egg laying.
  mRNA epigenetics: Charaterization of a novel layer of gene regulation for essential brain functions
  Research Group: BBSRC MIBTP
  Dr M Soller, Dr PG Grzechnik
Applications accepted all year round

Funding Type

PhD Type

For over 40 years we know about modified nucleotides in mRNA, but the functions for these essential modifications are largely elusive.
  Multimerisation of ELAV/Hu proteins – a key mechanism ensuring specificity for RNA recognition in health and disease
  Dr M Soller, Dr T Knowles
Applications accepted all year round

Funding Type

PhD Type

Aims. Determine the structure of the ELAV dodecameric complex bound to target RNA by cryoEM and functionally probe interaction interfaces in vitro and in vivo in transgenic Drosophila models for neurodegeneration and cancer.
  Neural basis underlying mating decisions in fruit flies
  Dr C Rezaval
Applications accepted all year round

Funding Type

PhD Type

Mate choice is an essential behavioural process with profound consequences in evolution. How do animals choose with whom to mate? How do they evaluate the features of a potential mate to maximise their reproductive success?.
  Statistical and Molecular Genetics of Complex Traits
  Prof Z Luo
Applications accepted all year round

Funding Type

PhD Type

Most characters of any living organism are polygenically controlled and environmentally modified, including those threatening human health and those important in breeding for high yield, better quality and improved adaption of animals, plants and microbes.
  Statistical genetics and genomics of complex traits
  Dr L Leach, Prof Z Luo
Applications accepted all year round

Funding Type

PhD Type

A highly motivated student is sought to train as a statistical geneticist working on the dissection of complex trait phenotypes in human, plant and animal populations into their underlying genetic components.
  Statistical methods for integrating multi-omics sequence data and unveiling molecular underpinnings of non-small cell lung cancer
  Prof Z Luo, Dr L Leach
Applications accepted all year round

Funding Type

PhD Type

The past decade has witnessed tremendous advancements in sequencing technologies, enabling collection of highly accurate and high resolution data on the structure and function of the genome.
  Structure and Function Studies on Proteins from Predatory Bacteria
  Dr A Lovering
Applications accepted all year round

Funding Type

PhD Type

Bdellovibrio bacteriovorus is a small predatory bacterium able to invade and kill many different Gram-negative bacterial prey (including human, animal and crop pathogens; e.g.
  Structure, Function and Biogenesis of the Mycobacterial Cell Wall
  Prof G Besra
Applications accepted all year round

Funding Type

PhD Type

There has been no significant decrease in worldwide mortality due to tuberculosis (TB) since before the time of Koch; the advent of sanatoria and chemotherapy, which drastically reduced TB in the more developed countries, has had no profound effect on the global problem.
  Understanding cholera pandemics
  Research Group: BBSRC MIBTP
  Dr D Grainger, Dr P A Lund
Applications accepted all year round

Funding Type

PhD Type

Vibrio cholerae is the causative agent of Cholera. Millions of cases of the disease occur every year and these are responsible for $3.1 billion dollar financial losses.
  Understanding the mechanism of action of ferro-nucleobase analogues
  Dr N J Hodges
Applications accepted all year round

Funding Type

PhD Type

Through collaboration with Professor Jim Tucker (School of Chemistry) we are studying the cellular effects of a novel DNA base analogues based on the organometallic compound ferrocene.
  Understanding the role of the globin cytoglobin in cancer cell drug resistance
  Dr N J Hodges
Applications accepted all year round

Funding Type

PhD Type

Cytoglobin is related to haemoglobin and myoglobin but has a very poorly understood biological function. Work in our lab has shown that expression of cytoglobin in cancer cells alters mitochondrial function and affords protection from anti-cancer drugs including cisplatin.
  Why do some DNA sequences poison cells?
  Research Group: BBSRC MIBTP
  Dr D Grainger
Applications accepted all year round

Funding Type

PhD Type

Life on our planet is permitted by an ancient set of instructions encoded by DNA. Consequently, the observation that a cell can be poisoned by its own DNA is completely counterintuitive.
  Designing sensorial behaviour of Fabrics
  Dr Z Zhang
Application Deadline: 30 September 2019

Funding Type

PhD Type

EPSRC supported EngD. Designing sensorial behaviour of Fabrics. Dr Jason Zhang (Chem Eng, University of Birmingham). P&G (Newcastle).
  Development a portable fuel cell device as an APU system for heavy duty vehicles or power supply for portable applications
  Dr A El-Kharouf, Prof R Steinberger-Wilckens
Application Deadline: 30 September 2019

Funding Type

PhD Type

A funded project with an industrial sponsor. This project focuses on the development of a low weight, low volume portable fuel cell device that can be used either as an APU system for heavy duty vehicles or power supply for portable applications.
  EPSRC supported EngD project. Modelling of wet milling.
  Prof S Blackburn
Application Deadline: 31 October 2019

Funding Type

PhD Type

Wet milling is a key production operation that is utilised to control particle size distribution (PSD) in slurry materials.
  EPSRC supported Engineering Doctorate. Prediction of complex industrial flows in the transitional regime.
  Prof M Simmons
Application Deadline: 31 October 2019

Funding Type

PhD Type

Whilst the simulation of flow in industrial reactors is now relatively well mastered for a wide range of chemical and process engineering applications, there are still several areas that require research effort, including the simulation of multiphase flows, flows with complex rheology and microstructure, and transitional flows (i.e.
  EPSRC supported PhD with Integrated Studies. Improving Efficiency of Screening and Optimizing Processes for the Development of Specialty Chemicals – a ‘bottom-up’ Methodology
  Dr Z Zhang
Application Deadline: 31 October 2019

Funding Type

PhD Type

Innospec and University of Birmingham, Chemical Engineering. Dr Zhenyu J Zhang & Prof. Jon Preece. Tax free bursary of approx. £16,000 p.a.
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