Norwich Research Park Featured PhD Programmes
Xi’an Jiaotong-Liverpool University Featured PhD Programmes
Norwich Research Park Featured PhD Programmes

University of Cambridge PhD Projects, Programs & Scholarships

We have 71 University of Cambridge PhD Projects, Programs & Scholarships

Discipline

Discipline

All disciplines

Location

Location

All locations

Institution

Institution

University of Cambridge

PhD Type

PhD Type

All PhD Types

Funding

Funding

All Funding


We have 71 University of Cambridge PhD Projects, Programs & Scholarships

PhD saved successfully

Using stem cells to probe virus infections of neurons

The consequences of virus infections in the brain can be devastating. This project will use cutting-edge stem cell, proteomics and imaging technologies to probe the effects of virus infection upon neurons, focussing on the neurotropic herpesvirus HSV-1. Read more

Defining the role of CRL Ub ligases in Plasmodium sexual differentiation and transmission

Ubiquitin and Nedd8 are involved in fundamental cellular processes and are essential to all eukaryotes. As such, enzymes mediating their dynamic attachment and removal from substrates present attractive targets for therapeutic intervention for both chronic and communicable diseases. Read more

Histone lactylation: a novel epigenetic feature in malaria parasites?

This project will investigate a new epigenetic modification in the human malaria parasite Plasmodium. Epigenetic marks, such as histone acetylation and methylation, play particularly important roles in virulence processes in this parasite – such as the switching and silencing of virulence genes. Read more

Exploring the Molecular Architecture of FADD:Caspase-8 Signalling Platforms and how this determines cell fate

 Following exposure to drugs or environmental agents, several large multi-protein signalling platforms play a key role in determining cell death or survival. Caspase-8, a key regulator of cell fate, is recruited/activated within these complexes; for example, the Death-Inducing Signalling Complex (DISC), Necrosome and Ripoptosome. Read more

Exploring the Molecular Mechanism of Novel Mitochondrial Neurotoxins identified through a Machine Learning Approach

Mitochondrial inhibition is an important ‘OFF-target’ mechanism of drug-induced toxicity in the clinic, contributing to drug attrition in clinical trials and drug withdrawal following approval because of severe adverse events (Will & Dykens, 2014). Read more

Nanometer scale mapping as a tool to analyse adverse outcome pathways

Super-resolution fluorescence microscopy has revolutionized the understanding of cellular organization by allowing quantitative analysis of protein assemblies architecture, in situ, at the nanoscale (Sydor et al. Read more

Characterization of novel airway in vitro models for discovery toxicology

The cellular and molecular mechanisms of human lung development are only recently beginning to emerge. This knowledge gap has been mainly determined by the paucity of ex vivo material for research studies and the lack of adequate animal models recapitulating human lung development (Nikolic et al. Read more

Filtering Results