The process to develop new medicines stars with the identification of small molecules that can modulate a biological target or pathway associated to the disease.
Amyotrophic Lateral Sclerosis (ALS) is caused by the breakdown of upper and lower motor neurons leading to the progressive weakness and atrophy of muscle, often resulting in respiratory failure and death within a few years of diagnosis.
There is an increasing interest in equipping our learners with the tools to be able to respond to change (1). The view that entrepreneurship education should be based on experiential approaches to learning is gaining ground.
The ageing process in health is one of main research topics currently and in the near future. The key icon for ageing in health is daily movements, e.g.walking.
Background. Acute pain is intrinsically unpleasant and aversive but is useful as it has survival benefit. However, many people suffer from chronic treatment-resistant pain that lasts months or years, lacks survival benefit, seriously impairs quality of life and causes unnecessary suffering.
In neurodegenerative disorders like Alzheimer’s disease (AD), synaptic communication within brain networks are impaired leading to significant memory deficits and dementia.
Squamous cell carcinomas across multiple sites (lung, head and neck, skin, oesophagus) represent the most frequent human malignancies and are a major cause of cancer mortality with limited therapeutic options for advanced disease.
