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University of Leeds PhD Projects, Programs & Scholarships

We have 55 University of Leeds PhD Projects, Programs & Scholarships

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I am a European student


We have 55 University of Leeds PhD Projects, Programs & Scholarships

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Understanding and controlling Beta-strand mediated protein-protein interactions using bespoke chemical modifications

Chemical probes are advantageous in studying the molecular mechanisms of health and disease; they uniquely allow temporary and titratable modulation of a target protein’s function, permitting evaluation of its functional role. Read more

What role do potassium ions play in the trafficking and function of proteins in the endocytic pathway?

The endocytic pathway plays a central role in cellular physiology, and is responsible for the uptake of extracellular material and molecules from the plasma membrane. Our recent work has established that potassium ions in the endosomal pathway are required for the infection of cells by a number of viruses. Read more

Probing a novel allosteric binding site in Mycobacterium DNA gyrase to tackle TB and antimicrobial resistance

Human pathogenic bacteria, e.g. Mycobacterium tuberculosis (TB), show increasing resistance to current antibiotics. Antimicrobial resistance (AMR) is probably the biggest current threat to human health; it is estimated that 10 million people per year could die because of AMR by 2050. Read more

Trapping BAM in action: A target for the development of new antibacterial strategies

Antibiotic resistance by gram-negative bacteria is a significant challenge, with pathogens of this class comprising 9 of the 12 bacteria that pose the greatest threat to human health, as identified by the World Health Organisation. Read more

Navigating through sequence space to understand Alpha-Synuclein Aggretion

The aggregation of the 140 residue protein a-synuclein into amyloid fibres is associated with neurodegenerative diseases known as synucleinopathies including Parkinson’s disease (the second most common neurodegenerative disease worldwide). Read more

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