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University of Manchester cancer PhD Projects, Programs & Scholarships

We have 39 University of Manchester cancer PhD Projects, Programs & Scholarships

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  Preparation, characterisation and application of advanced magnetic nanodiscs for cancer therapy
  Prof T Thomson
Applications accepted all year round
Supervisors. Tom Thomson (NEST) in collaboration with Neil Telling (Keele). Advances in conventional cancer treatments such as chemotherapy and radiotherapy have provided vast improvements in cancer survival rates over recent years.
  (A*STAR) Can non-coding variants explain missing heritability in familial cancer?
  Prof B Newman, Prof G Evans, Dr M Smith
Application Deadline: 31 January 2019
Heterozygous germline variants in a number of tumour suppressor genes cause a spectrum of familial cancers, including early onset breast-ovarian cancer, and colorectal cancer.
  A functional proteomic approach to reveal how receptor tyrosine kinases trafficking specifies cancer cell responses
  Dr C Francavilla, Prof S Hubbard
Applications accepted all year round
Background and goals. Cells respond appropriately to their surroundings by activating plasma membrane spanning receptors like Receptor Tyrosine Kinases (RTKs) and thereby adapting long-term outputs (e.g.
  ERK5 drives immune suppression in cancer
  Dr C Tournier, Dr K Finegan
Applications accepted all year round
The inflammatory microenvironment is arguably one of the most influential components of most, if not all, tumours (1).
  Controlling cancer: a new perspective to uncover tumor growth patterns
  Dr E Navarro-Lopez
Applications accepted all year round
Although the combination of control theory, dynamical systems analysis and systems biology has the potential to reveal important patterns in cancer evolution, it is not widely used.
  Developing preclinical models for cancer therapeutics using biomaterials and omics technologies
  Prof A Nicolaou, Dr A Tirella
Applications accepted all year round
Hydrogels are biomaterials used to prepare in vitro models used to study many biological processes. These materials can be selectively modified to present different physical, chemical and mechanical properties to mimic the ones of the extracellular matrix present in different tissues.
  (BBSRC DTP CASE) Development of novel peptide hydrogel therapies for endometriosis and endometrial cancer
  Prof K Marshall, Prof A Miller, Dr D Fischer
Application Deadline: 31 January 2019
Background. Endometrial cancer and endometriosis are common gynaecological disorders, which arise from the uterine lining. Cancer develops by glandular cell differentiation, whilst implantation and growth of endometrial-like tissue in endometriosis induces a chronic inflammatory reaction causing pain and infertility.
  New insights into cell cycle-dependent control of transcription: implications for cancer
  Prof A Sharrocks, Dr P Shore
Applications accepted all year round
Defects in the cell cycle are the underlying basis to cancer. Work in my lab is aimed at understanding the molecular basis to tumourigenesis through studying pathways which impact on the cell cycle and are deregulated in cancer.
  (A*STAR) Analysis of the role of microRNAs in the regulation of NF-kappaB dynamics and function
  Prof M White, Dr A P Gilmore
Application Deadline: 31 January 2019
The project will investigate the control of NF-kB. This transcription factor is one of most important cell signalling systems in the body that controls inflammation and cell fate.
  Very High Energy Electron (VHEE) Radiotherapy: A Potential New Paradigm in Cancer Treatment
  Prof R M. Jones, Dr D Angal-Kalinin, Dr A Subiel
Applications accepted all year round
We seek a candidate to work on dose studies and machine optimisation for VHEE treatment, a potential new paradigm in radiotherapy.
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