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University of Manchester PhD Projects, Programs & Scholarships

We have 389 University of Manchester PhD Projects, Programs & Scholarships

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Showing 41 to 50 of 389
  (BBSRC DTP) Integrating mechanical and biochemical signals in cell migration through membrane dynamics
  Dr P Caswell, Dr J-M Schwartz, Dr C Francavilla
Application Deadline: 31 January 2019
Cells respond to a myriad of cues from their environment, including mechanical signals from the extracellular matrix and biochemical cues from growth factors and cytokines.
  (BBSRC DTP) Integrative statistical inference methods for eukaryotic gene regulation with applications to embryonic stem cell differentiation
  Prof M Rattray, Dr I Iqbal, Prof A Sharrocks
Application Deadline: 31 January 2019
Embryonic stem cells (ESCs) can differentiate into different cell types through intermediary cell states and deeper understanding of the regulatory control underlying these differentiation stages is a very important topic in the study of mammalian development (Yang et al., 2014).
  (BBSRC DTP) Isothermal Amplification for viral detection
  Dr S Jones, Prof P Vallely
Application Deadline: 31 January 2019
The need to develop better techniques capable of improving detection of viral infections, whilst also improving the assays associated with identifying suitable antivirals is of upmost importance.
  (BBSRC DTP) Listeria monocytogenes in transit in the small intestine-interactions with the host mucosal surface and the host microbiota.
  Prof I Roberts, Prof D Thornton, Dr P Paszek
Application Deadline: 31 January 2019
Listeria monocytogenes is an opportunistic food borne pathogen responsible for a number of life threatening infections with a highest morality rate of any food borne bacterial pathogen.
  (BBSRC DTP) Metal handling systems in metal-reducing bacteria: Application to engineering high activity biometallic catalysts for clickable chemistries
  Dr J Cavet, Prof J Lloyd, Prof N Turner
Application Deadline: 31 January 2019
This project will contribute to a multidisciplinary research team focussed on the development of a new approach to making high value chemicals for a range of industries (including pharmaceuticals), in the vibrant and rapidly developing area of industrial biotechnology.
  (BBSRC DTP) Microbial population diversity as a driver of antibiotic resistance evolution
  Dr D Gifford, Dr C Knight, Dr T Gilman
Application Deadline: 31 January 2019
Classically, microbial evolution has been thought to progress via rapid sweeps of beneficial mutations that quickly fix within populations—the so-called ‘strong selection, weak mutation’ model.
  (BBSRC DTP) Morphological control of cell fate, behaviour and function
  Dr S Herbert, Prof N Papalopulu, Dr M Baron
Application Deadline: 31 January 2019
Tissue formation critically depends on the appropriate assignment of specialised cell fates and behaviours. The traditional perspective of these competitive decisions is that cells first perceive extrinsic signalling cues, decide their fate and then act appropriately (i.e.
  (BBSRC DTP) Partitioning primary and secondary changes of gene expression caused by gene mutations
  Dr D Talavera, Prof G D Pavitt, Dr J-M Schwartz
Application Deadline: 31 January 2019
Control of gene expression is a complex cell process, which involves balancing both the synthesis and the degradation of RNA and protein so as to establish optimal levels of each protein.
  (BBSRC DTP) Probing Regulatory Networks setting Notch signalling levels in vivo in Drosophila and Zebrafish.
  Dr M Baron, Dr S Herbert, Prof S Hubbard
Application Deadline: 31 January 2019
Development of organisms and maintenance of healthy tissues depends on proper control of cell to cell communication networks that control cell fate and behaviour.
  (BBSRC DTP) Stratification of nucleus pulposus cell sub-populations during intervertebral disc development, ageing and degeneration.
  Dr S Richardson, Prof J Hoyland
Application Deadline: 31 January 2019
Back pain is a leading cause of disability in the UK and intervertebral disc (IVD) degeneration has been identified as the cause in a high proportion of patients.
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