Pharmaceutical Chemistry (bradford) PhD Projects, Programmes & Scholarships

We have 10 Pharmaceutical Chemistry (bradford) PhD Projects, Programmes & Scholarships

New Drugs for Brain Tumours: Prodrugs of Diazopropyne

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

The propargyl group, introduced to temozolomide-like drugs for brain tumours by our colleagues in Nottingham, shows considerable pre-clinical promise and… Read more

Supervisors: Dr R Wheelhouse, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more

Supervisors: Dr R Wheelhouse, Dr S Shnyder, Dr A Ramachandra Kurup Sasikala

Year round applications PhD Research Project Self-Funded PhD Students Only

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Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

Supervisor: Dr Muhammad Wahajuddin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Therapeutic resolution of Myelodysplastic Syndrome (MDS) by natural products

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Myelodysplastic syndromes (MDS) are a type of blood cancer where the patients do not have enough healthy blood cells. Read more

Supervisors: Dr T Nasim, Dr M Najafzadeh

Year round applications PhD Research Project Self-Funded PhD Students Only

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Directed Co-Crystallisation of Pharmaceuticals: developing a predictive method for co-crystallisation

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

In this project, we propose to use a combination of computational and experimental techniques to develop a predictive method for co-crystallisation. Read more

Supervisor: Dr C Seaton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Supervisors: Prof R Falconer, Prof P Loadman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Therapeutic resolution of BMPR2-mediated signalling defects in pulmonary arterial hypertension (PAH)

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Pulmonary arterial hypertension (PAH) is an incurable and devastating disease and death occurs within 2.5 years of diagnosis. Read more

Supervisors: Dr T Nasim, Dr R Gopalan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identifying cognitive and biochemical changes underlying lifestyle risk factors for dementia

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Dementia describes a group of age-associated conditions of which cognitive decline is a major feature. Alzheimer’s disease (AD) is the most common cause of dementia and is characterised by the onset of a gradual cognitive decline. Read more

Supervisors: Dr S McLean, Dr R Williamson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

Supervisors: Prof R Falconer, Dr S Shnyder

Year round applications PhD Research Project Self-Funded PhD Students Only

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Biological rhythms and the dopamine system in cognitive dysfunction

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Psychiatric disorders such as schizophrenia are associated with metabolic syndrome, obesity and diabetes. Schizophrenia affects 1.1% of the population and although not the most common psychiatric condition it is arguably the most severe and debilitating. Read more

Supervisors: Dr S McLean, Dr G Helfer

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 10 Pharmaceutical Chemistry (bradford) PhD Projects, Programmes & Scholarships

Pharmaceutical Chemistry (bradford) PhD Projects, Programmes & Scholarships

We have 10 Pharmaceutical Chemistry (bradford) PhD Projects, Programmes & Scholarships

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