Pharmaceutical Chemistry (cell engineering) PhD Projects, Programmes & Scholarships

We have 12 Pharmaceutical Chemistry (cell engineering) PhD Projects, Programmes & Scholarships

EPSRC CDT in Bioprocess Engineering Leadership: Complex Biological Products Manufacture

University College London Department of Biochemical Engineering

Biological products and their manufacture are progressing to unparalleled levels of complexity. Examples include engineered biocatalysts, antibody-drug conjugates, multivalent vaccines and cellular therapies. Read more

Funded PhD Programme (UK Students Only) EPSRC Centre for Doctoral Training

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High-throughput characterization and engineering of nucleotide synthases for production of nucleoside analogues

The University of Manchester Department of Chemistry

Nucleotides are the building blocks of life, modulating diverse processes from protein production to cell signalling. It is therefore unsurprising that synthetic nucleoside analogues have been developed as therapeutics for the treatment of a wide range of diseases including cancers and viral infections. Read more

Supervisors: Dr S Lovelock, Dr C Markin

31 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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New strategies to cryopreserve cell-based therapies

The University of Manchester Department of Chemistry

In the past decade, cell-based therapies have emerged to transform the treatment of disease, particularly cancer. Whilst potent, these therapies are challenging to deliver in practise as must be stored frozen (cryopreserved). Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Designing Peptide hydrogels as vehicles for targeted and localised in-vivo therapeutics delivery

The University of Manchester Faculty of Biology, Medicine and Health

One of the key engineering challenges in the life-science and biomedical sectors is the design and manufacturing of bespoke hydrogels for 3D cell culture, tissue engineering and cell/drug delivery. Read more

Supervisors: Prof A Saiani, Dr K Finegan

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Targeting glycans on the outside of cells, as new therapeutics

The University of Manchester Department of Chemistry

Most drugs have intracellular targets (proteins etc). This creates a barrier to how to target a cell, and then get the drug inside the cell. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Intelligent Biosensing Systems for Healthcare

University of Southampton Faculty of Engineering and Physical Sciences

Supervisory Team: Dr Chengchen Zhang, Prof Hywel Morgan. Project description. Read more

Supervisor: Dr C Zhang

31 August 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Protein self assembly induced by multivalent biological metabolites

The University of Manchester Department of Chemical Engineering

In addition to being an energy source in biological reactions, recent discoveries suggest adenosine triphosphate (ATP) also plays a critical role in maintaining cell stability and preventing deleterious cellular processes through modulating biomacromolecular self assembly. Read more

Supervisor: Dr R Curtis

31 December 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

Supervisor: Dr Muhammad Wahajuddin

Year round applications PhD Research Project Self-Funded PhD Students Only

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(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

The University of Manchester Department of Chemistry

Ecteinascidin 743 (ET-743, Trabectedin) is a marine-derived natural organic compound approved for the treatment of soft tissue sarcomas. Read more

Supervisors: Prof E Takano, Prof H Oguri

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Elucidating the role of lipids in fibrotic capsule formation at the surface of implanted medical devices.

University of Nottingham School of Medicine

Implanted medical devices are crucial in healthcare, valued at around £400 billion globally, however there is a high failure rate, often due to the foreign body reaction, where a fibrotic capsule forms around the implant with associated inflammation, loosening and infection. Read more

Supervisors: Prof M Alexander, Prof AG Ghaemmaghami, Dr D H Kim, Prof BO Ollivere

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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New Drugs for Brain Tumours: Defining the Physicochemical Parameters for Optimal Imidazotetrazine (Temozolomide) Derivative Prodrug Activation Kinetics

University of Bradford Faculty of Life Sciences

Research Group: Medicines Development and Pharmaceutical Sciences

The imidazotetrazine ring system that forms the core of the anticancer drug temozolomide is a fascinating prodrug delivery device. Read more

Supervisors: Dr R Wheelhouse, Dr S Shnyder, Dr A Ramachandra Kurup Sasikala

Year round applications PhD Research Project Self-Funded PhD Students Only

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Synthetic Protein-Transporters for Enhanced Transduction Activity

Queen’s University Belfast School of Pharmacy

Intracellular protein delivery is key to probing important cellular processes and developing advanced biotherapeutics. However, protein trafficking into the cell, and more specifically to the cytosol remains a significant challenge. Read more

Supervisor: Dr S Carmali

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 12 Pharmaceutical Chemistry (cell engineering) PhD Projects, Programmes & Scholarships

Pharmaceutical Chemistry (cell engineering) PhD Projects, Programmes & Scholarships

We have 12 Pharmaceutical Chemistry (cell engineering) PhD Projects, Programmes & Scholarships

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