Continue with FacebookLooking to list your PhD opportunities? Log in here.
University of York, York Biomedical Research Institute PhD Projects, Programmes & Scholarships
We have 18 University of York, York Biomedical Research Institute PhD Projects, Programmes & Scholarships
We have 18 University of York, York Biomedical Research Institute PhD Projects, Programmes & Scholarships
PhD saved successfully
Self funded BMS Project_Investigating the Effects of Glucocorticoids on the Development of Lab Grown Mini-brains.
Glucocorticoids are some of the most commonly prescribed therapeutics worldwide because of their low-cost and anti-inflammatory effects. Read more
Self funded BMS Project : A nuclear enterprise: characterisation of an antigen expression factory for immune evasion in African trypanosomes
Applications accepted for PhD Only. Antigenic variation is a highly sophisticated virulence mechanism. Several pathogens, such as African trypanosomes and malaria parasites, are able to systematically alter the identity of proteins displayed to the host immune system. Read more
Self funded BMS Project: Role of the endosomal pathway in regulating sleep and circadian rhythms
Applications accepted for PhD Only. Ageing and many neurodegenerative disorders are characterized by a progressive loss of neurons in particular brain regions leading to behavioural changes including cognitive decline, sleep disruption and circadian dysregulation. Read more
Self funded BMS Project: Innate immune responses in aymotrophic lateral sclerosis and frontotemporal dementia.
Applications accepted for PhD Only. Neurons express an innate immune response cascade to regulate synaptic homeostasis. We have identified activation of components of this innate immune cascade in response to amyotrophic lateral sclerosis (ALS) and frontotemporal dementia associated (FTD) mutations. Read more
Self funded BMS Project: Neuronal-Src kinases: oncogenes in brain development?
Applications accepted for PhD Only. The challenges of the developing human brain include co-ordinating the birth and migration of 100 billion neurons and the formation of their 1000 trillion synaptic connections. Read more
Self funded BMS Project: Parasite behaviour analysis using artificial intelligence
Applications accepted for PhD Only. Early diagnosis of bacterial or parasitic infections optimises the patient’s chances of survival. Read more
Self funded BMS Project: Tissue-specific roles of human endogenous retroviruses in urothelial carcinoma
Applications accepted for PhD Only. Human endogenous retroviruses (HERVs) are the remnants of retroviral infections in our evolutionary past that contribute 8% of our genome. Read more
Self funded BMS Project: Understanding normal and malignant blood stem cell biology
Applications accepted for PhD Only. Background. Haematopoiesis is a complex, finely-tuned process that produces trillions of new blood cells daily. Read more
Self funded BMS Project: Understanding the population dynamics of haematopoietic stem cells during gene therapy for sickle cell disease
Applications accepted for PhD Only. Background. This project builds on the recent discovery that whole genome sequencing approaches in blood stem and progenitor cells can be used to estimate the number of actively contributing blood stem cells in humans (Lee-Six et al., Nature 2018). Read more
Self funded BMS Project: Autophagic control of cellular rejuvenation and the reversal of cell ageing
Applications accepted for PhD Only. The percentage of national populations over the age of 65 has been increasing and by 2050 the number of adults over the age of 80 is expected to triple. Read more
Self funded BMS Project: Assessing the emergence of transient, growth related antibiotic resistance in bacterial populations
Applications accepted for PhD Only. Antimicrobial resistance (AMR) is a significant concern in the battle against bacterial disease. Read more
Self Funded BMS Project: Fragment-Based Lead Generation of Small Molecule Inhibitors of the Nsp3 Macrodomain in SARS-CoV-2 – Towards New Antivirals for the Treatment of COVID-19
Applications accepted for PhD Only. Background. Coronaviruses (CoVs) are important human pathogens and SARS-CoV-2 is responsible for the current COVID-19 pandemic (>260m cases, 5.2m deaths). Read more
Self funded BMS Project: Harnessing ion channels in immune cells to promote tumour suppression
Applications accepted for PhD Only. A complex network of interactions between different immune cell subsets orchestrates timely and tightly controlled immune responses. Read more
Self funded BMS Project: The impact of type 2 immunity on haematopoiesis and consequences for host immune function
Applications accepted for PhD Only. Haematopoietic stem cells (HSCs) sense peripheral inflammation allowing immune cell production in the bone marrow to be tailored to ongoing demands. Read more
Self funded BMS Project: RNA dysregulation in neurodegeneration
Applications accepted for PhD Only. Neurodegenerative diseases are characterised by progressive neuronal loss with no effective treatment available. Read more
- 1
- 2