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University of York, York Biomedical Research Institute PhD Projects, Programmes & Scholarships

We have 18 University of York, York Biomedical Research Institute PhD Projects, Programmes & Scholarships

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York Biomedical Research Institute  University of York

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We have 18 University of York, York Biomedical Research Institute PhD Projects, Programmes & Scholarships

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Self funded BMS Project : A nuclear enterprise: characterisation of an antigen expression factory for immune evasion in African trypanosomes

Applications accepted for PhD Only. Antigenic variation is a highly sophisticated virulence mechanism. Several pathogens, such as African trypanosomes and malaria parasites, are able to systematically alter the identity of proteins displayed to the host immune system. Read more

Self funded BMS Project: Role of the endosomal pathway in regulating sleep and circadian rhythms

Applications accepted for PhD Only. Ageing and many neurodegenerative disorders are characterized by a progressive loss of neurons in particular brain regions leading to behavioural changes including cognitive decline, sleep disruption and circadian dysregulation. Read more

Self funded BMS Project: Innate immune responses in aymotrophic lateral sclerosis and frontotemporal dementia.

Applications accepted for PhD Only. Neurons express an innate immune response cascade to regulate synaptic homeostasis. We have identified activation of components of this innate immune cascade in response to amyotrophic lateral sclerosis (ALS) and frontotemporal dementia associated (FTD) mutations. Read more

Self funded BMS Project: Neuronal-Src kinases: oncogenes in brain development?

Applications accepted for PhD Only. The challenges of the developing human brain include co-ordinating the birth and migration of 100 billion neurons and the formation of their 1000 trillion synaptic connections. Read more

Self funded BMS Project: Understanding the population dynamics of haematopoietic stem cells during gene therapy for sickle cell disease

Applications accepted for PhD Only. Background. This project builds on the recent discovery that whole genome sequencing approaches in blood stem and progenitor cells can be used to estimate the number of actively contributing blood stem cells in humans (Lee-Six et al., Nature 2018). Read more

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