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Chemical Sciences PhD Projects, Programs & Scholarships in York

We have 44 Chemical Sciences PhD Projects, Programs & Scholarships in York

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Showing 1 to 15 of 44
  Photochemical Pathways of Photoinitiators: a Study for Inkjet Applications and Beyond
  Dr J N Moore, Prof S Duckett
Application Deadline: 24 July 2020

Funding Type

PhD Type

This PhD project will explore the mode of action of the latest generation of organic photoinitiators used in industrial UV inkjet printing and beyond.
  Insights into the mechanism of lytic polysaccharide monooxygenases through EPR, resonance Raman and X-ray Absorption and Emission spectroscopies
  Prof P Walton
Application Deadline: 11 June 2020

Funding Type

PhD Type

This project is a collaboration between the University of York and Diamond Light Source Ltd. The supervisor at Diamond will be Dr Sofia Diaz-Moreno.
  Observing Nucleic Acid Aptamer Binding with Ultrafast 2D-IR Spectroscopy
  Prof N Hunt
Applications accepted all year round

Funding Type

PhD Type

The project will be a collaboration with Prof Glenn Burley (University of Strathclyde). Background. The strong and specific binding of small molecules and proteins to DNA has relevance across many areas, from fundamental biophysics, through chemical biology to nanotechnology.
  Design and Synthesis of Bifunctional 3-D Building Blocks for Use in Medicinal Chemistry
  Prof P O'Brien
Applications accepted all year round

Funding Type

PhD Type

This project is in collaboration with Professor Mike Waring (Newcastle University). Background. Fragment-based methods are established for the identification of lead compounds in drug discovery.1 Fragments are small molecules (molecular weight ~150-300) which bind weakly to proteins.
  Development of magnetic nanoparticles for improved targeted delivery of growth factors
  Dr V Chechik
Applications accepted all year round

Funding Type

PhD Type

Background. Magnetic nanoparticles (MNPs) can be heated by applying oscillating magnetic field. MNPs can hence be used to thermally destroy biological tissue (e.g., cancer cells) by remote magnetic activation.
  Development of chemical biology tools to study mammalian O-mannosylation pathways
  Dr L Willems, Prof G Davies
Applications accepted all year round

Funding Type

PhD Type

The field of chemical biology aims to design and synthesize chemical tools (such as inhibitors, substrate mimics, or enzyme probes) to answer fundamental questions in biology.
  New Routes to Cyclic Sulfoximine 3-D Fragments for Medicinal Chemistry
  Prof P O'Brien
Applications accepted all year round

Funding Type

PhD Type

Background. The sulfoximine functional group is becoming increasingly popular within medicinal chemistry groups – notably, sulfoximines have featured in potential cancer treatments in clinical trials such as AZD6738 developed by AstraZeneca.
  Towards Understanding of the Photodegradation Pathways in Lignins
  Dr MCR Cockett
Applications accepted all year round

Funding Type

PhD Type

Lignins are amongst the most abundant biopolymers on Earth, and are key components of the cell walls of many vascular plants. However, our fundamental knowledge of the photochemistry of the molecular building blocks that make up lignins (i.e.
  Exploring the fundamental reactivity of different species present in “GaOTf” to understand better how they may play a role in catalysis
  Dr J Slattery
Applications accepted all year round

Funding Type

PhD Type

There has been a recent renaissance in main group chemistry that has led to a number of new, high-profile research areas, including frustrated Lewis pair (FLP) chemistry and many more.
  Investigating the addition of hydrogen to transition metal centres in conjunction with NMR spectroscopy and photochemistry within an NMR probe
  Prof S Duckett
Applications accepted all year round

Funding Type

PhD Type

Strategy. The aim in this project is to investigate the addition of hydrogen to transition metal centres in conjunction with NMR spectroscopy and photochemistry within an NMR probe.
  Extending the use of time-resolved electron diffraction to perform pump-probe experiments for molecular species
  Dr D A Wann
Applications accepted all year round

Funding Type

PhD Type

The Wann group has a time-resolved electron diffraction apparatus in York capable of time resolution of around 1 ps. We also use the Stanford ultrafast election diffraction set-up for 100 fs time resolution experiments.
  Developing dual-mode therapeutic systems to attack cancer tumours
  Prof D K Smith
Applications accepted all year round

Funding Type

PhD Type

Cancer is a challenging disease target, requiring wide-ranging strategies for intervention. Given the difficulties in treating recalcitrant tumours, multi-mode therapies are of significant potential value.
  How the chemistry used to attach proteins to biomaterial surfaces influences how cells grow
  Dr C Spicer
Applications accepted all year round

Funding Type

PhD Type

Background. The use of synthetic materials as scaffolds for growing cells and tissues is a key concept in tissue engineering. Tissues grown in the lab could potentially be used to repair damage in vivo for the treatment of disease.
  Obtaining a better understanding of the identity of agrichemical photoproducts
  Dr C E Dessent
Applications accepted all year round

Funding Type

PhD Type

Background. Agrichemicals are widely used to to protect crops from pests and enhance crop yields, but represent an important class of potential environmental contaminants.
  Photocatalytic solar energy conversion
  Dr R E Douthwaite
Applications accepted all year round

Funding Type

PhD Type

There is a clear need to develop processes that minimise the consumption of limited energy resources and reduce waste detrimental to the environment.
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