The Role of Rho Family GTPases in Glioma

Gliomas are the commonest form of brain tumour and the progression from low to high grade malignant glioma is associated with increased invasion and poor prognosis. Gliomas are difficult to treat and there is an urgent need to better understand factors that contribute to disease progression. The Rho family of small GTPases regulate play a pivotal role in regulating cell adhesion dependent functions such as cell migration and tumour cell invasion. Recently, we have identified that progression from low to high grade glioma is associated with one member of the Rho family called Rnd3 and this project will analyse how Rnd3 regulates progression from low to high grade glioma.

Please find additional funding text below. For further funding details, please see the ‘Funding’ section.
The School of Biosciences offers a number of UK Research Council (e.g. BBSRC, NERC) PhD studentships each year. Fully funded research council studentships are normally only available to UK nationals (or EU nationals resident in the UK) but part-funded studentships may be available to EU applicants resident outside of the UK. The deadline for applications for research council studentships is 31 January each year.

Each year we also have a number of fully funded Darwin Trust Scholarships. These are provided by the Darwin Trust of Edinburgh and are for non-UK students wishing to undertake a PhD in the general area of Molecular Microbiology. The deadline for this scheme is also 31 January each year.