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This project is to be funded under the MRC Doctoral Training Partnership. If you are interested in this project, please make direct contact with the Principal Supervisor to arrange to discuss the project further as soon as possible. You MUST also submit an online application form - full details on how to apply can be found on the MRC DTP website www.manchester.ac.uk/mrcdtpstudentships
Applications are invited from UK/EU nationals only. Applicants must have obtained, or be about to obtain, at least an upper second class honours degree (or equivalent) in a relevant subject.
Whole organ vascular casting and microCT examination of the human placental vascular tree reveals novel alterations associated with pregnancy disease.
Junaid TO, Bradley RS, Lewis RM, Aplin JD, Johnstone ED. Sci Rep. 2017 Jun 23;7(1):4144. doi: 10.1038/s41598-017-04379-0.
Integration of computational modeling with membrane transport studies reveals new insights into amino acid exchange transport mechanisms.
Widdows KL, Panitchob N, Crocker IP, Please CP, Hanson MA, Sibley CP, Johnstone ED, Sengers BG, Lewis RM, Glazier JD. FASEB J. 2015 Jun;29(6):2583-94. doi: 10.1096/fj.14-267773. Epub 2015 Mar 11.
Image-Based Modeling of Blood Flow and Oxygen Transfer in Feto-Placental Capillaries.
Pearce P, Brownbill P, Janáček J, Jirkovská M, Kubínová L, Chernyavsky IL, Jensen OE.
PLoS One. 2016 Oct 27;11(10):e0165369. doi: 10.1371/journal.pone.0165369. eCollection 2016.
Dysregulated flow-mediated vasodilatation in the human placenta in fetal growth restriction.
Jones S, Bischof H, Lang I, Desoye G, Greenwood SL, Johnstone ED, Wareing M, Sibley CP, Brownbill P.
J Physiol. 2015 Jul 15;593(14):3077-92. doi: 10.1113/JP270495. Epub 2015 Jun 8.
Optimal villi density for maximal oxygen uptake in the human placenta.
Serov AS, Salafia CM, Brownbill P, Grebenkov DS, Filoche M.
J Theor Biol. 2015 Jan 7;364:383-96. doi: 10.1016/j.jtbi.2014.09.022. Epub 2014 Sep 27.