Dr S Landolfo
No more applications being accepted
Funded PhD Project (Students Worldwide)
About the Project
Objectives
•To characterize the genetic variability of Human Cytomegalovirus (HCMV) from different clinical isolates and identify the mechanisms the virus relies on to escape the restriction activity of host factors
•To identify novel antiviral targets based on post-translational modifications exploited by HCMV during replication
Expected achievements
•Characterization of the viral DNA genes undergoing variability during the first steps of infection and their interaction with host restriction factors
•Characterization of the host restriction factors and the post-translational modifications they undergo during HCMV replication in both in vitro and in vivo models
•Novel antiviral drugs targeting post-translational modifications occurring during HCMV infection and essential for virus replication
Planned Secondments
•Helmholtz-Zentrum For Infection Research, Braunschweig, Germany; Evaluation of results in infections with cytomegalovirus
•JENA Biosciences GmbH, Germany; CLICK-based methods for labeling of viruses and cells
Requirements
•Solid background/expertise in cell biology, virology, and immunology
•Experience with mouse disease models
•Ability to manage large experimental setups
Appointment details
Based on a full-time appointment, the duration of the appointment as a Marie Curie ITN fellow will be for a maximum period of 3 years. The PhD student will become member of the Medical School, Turin University, Italy, and is expected to present her/his work at the annually PhD Day in the Medical School and to follow the mandatory training program.
Manadatory Eligibility Criteria
Mobililty Rule
The researcher must not have resided or carried out his/her main activity (work, studies, etc) in the country of his/her host organization for more than 12 months in the 3 years immediately prior to his/her recruitment. Short stays, such as holidays, are not taken into account.
Career Stage
Early stage researcher shall at the time of recruitment be in the first four years (full-time equivalent research experience) of their research careers and have not been awarded a doctoral degree.
Contact details
Santo Landolfo, Professor
Department of Public Health and Pediatric Sciences
School of Medicine
University of Turin
Italy
[Email Address Removed]
Funding Notes
Benefits
Monthly gross salary will be in accordance with the EC Marie Sklodowska Curie rates and will be paid by the host organization. The salary may be subjected to tax according to applicable national regulations. The positions are full-time and designed for a duration of 36 months.
Prospective date for start of project: Sep 1, 2016
The ESR cannot start before the project and candidate have been approved of the local PhD school as well as an approved residence and work permit (where applicable).
The ESR will be employed/enrolled locally in either Denmark, Germany, the Netherlands, United Kingdom, or Italy.
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