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Multiscale simulation of environment-induced conformational transitions in peptides: folding, partitioning and aggregation

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  • Full or part time
    Prof M Sayar
  • Application Deadline
    No more applications being accepted
  • Competition Funded PhD Project (Students Worldwide)
    Competition Funded PhD Project (Students Worldwide)

Project Description

Applications accepted until June 16, 2017

Competitive private sector funded project (open to 1 student from all nationalities)

About This PhD Project

Assembly of proteins and peptides plays an essential role in the structure and inner-workings of the cell. On the other hand, uncontrolled aggregation of peptides is seen as the source of Neurodegenerative diseases such as Alzheimer’s.

In this project our aim is to understand the aggregation mechanism of proteins and peptides and to develop new techniques for controlling and guiding this assembly process. In particular we are interested in the role of macroscopic and molecular hydrophobic/hydrophilic interfaces.

To this end we use atomistic and coarse-grained computer models to study the aggregation of these molecules. Within this project we are also collaborating with Prof. Christine Peter from University of Konstanz.

Successful candidates will be part of a vibrant group of researchers at the Computational Science and Engineering group at Koc University, Istanbul.

More information can be found here: http://home.ku.edu.tr/~msayar/

Email now

Contact the project director Prof. Sayar [email protected]

Funding Notes

This project is available to students who have completed a BSc or MSc in a related field applying for funded PhD studentships in the Phd in Computational Sciences and Engineering and may be altered or withdrawn.

Studentships will be awarded to successful applicants from all applications received. Applicants must satisfy all admission criteria required by the PhD program at the Graduate School of Sciences and Engineering. For more information please visit: https://gsse.ku.edu.tr/en/


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