Computational Modelling of Acoustic Cavitation in Skin Sonoporation

Our research is focused in computational analysis of acoustic cavitation in the application of Transdermal Drug Delivery. Specifically, we consider Computational Modelling of the effect of exposing the skin to an Ultrasound Frequency acoustic field in order to alter the barrier function of the skin. This is believed to be accomplished by the introduction of the cavitation of micro-bubbles near the surface of the skin.

The current work models the collapse of a gas bubble that is near the skin’s surface. The collapse is initiated by an oscillating pressure field to represent ultrasound. The subsequent fluid dynamics are captured and the inertial and thermal influences at the skin’s surface are considered. We are developing computational codes to run on the High Performance Computing Intel System Sandy Bridge.

This project group currently has 2 PhD students and the research is conducted in an international collaborative effort.

Required: Master’s Degree , Peer reviewed publications , Experience in computational code development (experience in source code development preferred: C++, FORTRAN).

Please include a copy of your CV and referees, academic transcript and details of any undergraduate or postgraduate degrees, and any evidence of research outputs to Dr. Sid Becker at: [Email Address Removed]