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  Development of Cu- and Ni-catalyzed C-C and C-X bond forming reactions for biomolecule synthesis


   Department of Pure and Applied Chemistry

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  Dr Allan Watson  Applications accepted all year round  Funded PhD Project (European/UK Students Only)

About the Project

Transition metal-catalyzed reactions are of vital importance for the synthesis of bioactive molecules.
This project has two main themes: (1) the development of new Cu- and Ni-catalyzed C-C and C-X bond forming reactions tailored towards processes of relevance to the pharmaceutical and agrochemical industries; and (2) determining the mechanism of these new reactions.

The ideal candidate will have a good knowledge of organic chemistry and catalysis with organometallic chemistry knowledge beneficial but not essential. Good interpersonal, presentation, scientific writing, and data handling skills are essential.

The project will provide a thorough training in organic synthesis, catalysis, physical-organic chemistry.

For examples of Watson Group research, see: watsonresearchgroup.co.uk


Funding Notes

A 2-1 degree classification or above is required. The position is for 48 months. UK/EU applicants only.
Please send your CV with the names of two referees to [Email Address Removed].

References

For selected papers relevant to this project, see:
(1) J. W. B. Fyfe, C. P. Seath, and A. J. B. Watson, Angew. Chem. Int. Ed., 2014, 53, 12077-12080.
(2) C. P. Seath, J. W. B. Fyfe, J. J. Molloy, and A. J. B. Watson, Angew. Chem. Int. Ed. 2015, 54, 9976–9979.
(3) C. W. Muir, J. C. Vantourout, A. Isidro-Llobet, S. J. F. Macdonald and A. J. B. Watson, Org. Lett. 2015, 17, 6030–6033.
(4) M. Z. C. Hatit, J. C. Sadler, L. A. McLean, B. C. Whitehurst, C. P. Seath, L. D. Humphreys, R. J. Young, A. J. B. Watson, and G. A. Burley, Org. Lett. 2016, 18, 1694–1697.
(5) J. J. Molloy, T. A. Clohessy, C. Irving, N. A. Anderson, G. C. Lloyd-Jones, and A. J. B. Watson Chem. Sci. 2016, DOI: 10.1039/C6SC04014D.

Where will I study?