Prof RA Quinlan
No more applications being accepted
Competition Funded PhD Project (European/UK Students Only)
About the Project
The project will employ all the available cutting-edge approaches to study structure-function relationships in a protein. It embraces the fusion of protein crystallography with cryoelectron microscopy, indeed we were one of the first groups to apply this to the extremophile small heat shock protein MjHSP16.5. The successful candidate will join groups (Quinlan/Lewis) internationally acclaimed for their work on the stress response in bacterial and mammalian systems respectively. Both have international connections and collaborations with academics and industry-linked scientists to maximize future career prospects and opportunities. The local interdisciplinary collaborations of the host labs connects their research and group members across departmental boundaries, so the successful candidate can benefit from the scrutiny and encouragement of multidisciplinary experts fascinated by key biological questions. Here the stress response is uppermost, especially as we try to understand the processes that retain protein function and so make a difference by development therapeutics to improve human health. Small heat shock proteins are conserved from microbes to man and mutations in these proteins accelerate ageing, cause disease in humans, whilst also allowing life to exist in the most inhospitable environment on and off (Ramazzottius varieornatus, space bear) the planet. sHSPs are hot!
For further information see the website: https://www.dur.ac.uk/biosciences/
To apply:
Please submit a full CV and covering letter directly to [Email Address Removed]
Funding Notes
This is a 4 year BBSRC studentship under the Newcastle-Liverpool-Durham DTP. The successful applicant will receive research costs, tuition fees and stipend (£14,296 for 2016-17). The PhD will start in October 2017. Applicants should have, or be expecting to receive, a 2.1 Hons degree (or equivalent) in a relevant subject. EU candidates must have been resident in the UK for 3 years in order to receive full support. There are 2 stages to the application process.
References
Sub-nanometre mapping of the aquaporin-water interface using multifrequency atomic force microscopy. Ricci M, Quinlan RA, Voïtchovsky K. Soft Matter. 2016 Jul 4. DOI: 10.1039/c6sm00751a
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