PhD Position in Enzyme Engineering - enzyme-based biosensors for use in biotechnological applications

In the Laboratory for Enzyme Engineering and Evolution, we are interested in questions at the intersection of biochemistry and evolutionary biology. What were the structures, functions and mechanisms of enzymes in the ‘primordial soup’? What mutations are required to change an enzyme with one function into another? And how can we use insights from evolution to design proteins with biomedical and biotechnological applications?

Dr. Wayne Patrick is currently seeking 1-2 enthusiastic and hard-working PhD students to join his group.

In this project, you will design and build enzyme-based biosensors for use in biotechnological (but not biomedical) applications. This project is in collaboration with Molecular Warehouse (http://molecularwarehouse.com/). You will use protein biochemistry, site-directed mutagenesis, protein design and a variety of assay/detection methods.

A background in (and fascination with) protein biochemistry is essential, while experience in biomolecular chemistry, microbiology and/or relevant areas of biotechnology would also be beneficial.

A second project option is listed here: https://www.findaphd.com/search/ProjectDetails.aspx?PJID=80608

The successful candidate will be supported through the University of Otago Doctoral Scholarship scheme. This provides a NZ$25,000 tax-free stipend per annum, plus all tuition fees, for 3 years (regardless of the nationality of the candidate).

Applicants must have a strong BSc (Hons) or MSc degree in a relevant discipline, as well as a willingness to learn, develop and apply new techniques. The start date is negotiable; students who are completing their degree this semester/term are welcome to apply.

To apply, please submit the following documents using the form below, or directly by email to [Email Address Removed]:

- A cover letter stating your interest in the position, and why you think you would be a good candidate.
- A curriculum vitae.
- A copy of your academic transcript (including a list of grades).
- The names of at least two academic referees.
- Evidence of English language proficiency. If English is not your first language, you must satisfy the University of Otago’s English language requirements (http://www.otago.ac.nz/international/postgraduate/index.html) in order to be considered.

More information about our laboratory, including our recent publications in the project area, can be found at www.enzymes.org.nz.