Dr V Bystrý, Prof S Pospíšilová
No more applications being accepted
Competition Funded PhD Project (Students Worldwide)
About the Project
The immunoglobulin superfamily of proteins is a group of recognition and signalling proteins expressed on cell surfaces. Analysis of immunoglobulin (IG) and T cell receptor (TR) repertoires – or immunoprofiling, has been instrumental in understanding a wide range of diseases with an underlying immune basis, such as lymphomas, infections, and allergies. With the introduction of next generation sequencing (NGS) methods, much more detailed insights are now available. However, this also poses unique challenges for sequence analysis due to the enormous inherent complexity, huge diversity and temporal variation of immune responses combined with imprecise and bias-prone nature of current NGS technologies. The aim of the PhD study will be to design, implement and apply in silico analytical methods for processing of NGS data from leukemia patient samples. The focus will be the recognition and quantification of repertoire abnormalities in general and the clonality assessment and MRD monitoring in particular.
All general enquiries should be directed to Olga Křížová ([Email Address Removed]). Scientific inquiries can be addressed to the supervisor ([Email Address Removed]).
Funding Notes
Admission for studies, student registration for the full-time study programme and proper fulfilment of student duties constitute the student’s right to a regular scholarship of 20 000 CZK (730 EUR). Information is available at http://ls-phd.ceitec.cz/information-for-students/#fund
Living costs and other practicalities available at http://ls-phd.ceitec.cz/practical-information-for-life-in-brno/
References
Applicants who wish to pursue a degree at the CEITEC PhD programme must hold the equivalent of a Master's degree (MSc) in the same or similar field (four or five year undergraduate degree). The application can be submitted before obtaining the Master's degree, however, the applicant should obtain the degree within five month after the application deadline.
Continue with Facebook
