PhD Organic Chemistry: New synthesis of benzene isosteres (EPSRC CASE award)

Benzene isosteres are of fundamental importance to the pharmaceutical and agrochemical industries due to 1) improved physical and biological properties and 2) increase of structural novelty for patents. Recent examples of such isosteres include azaborines and bicyclo[1.1.1]pentanes among others.

Building on our expertise in homogeneous catalysis and the activation of otherwise inert C-H and C-C bonds, we will now start a new adventure and develop novel approaches to important benzene isosteres in collaboration with Eli Lilly, AstraZeneca, Syngenta and LiverpoolChiroChem.

Our research programme is perfectly suited for the training of postgraduate students who desire to acquire an in-depth knowledge of cutting-edge transition-metal catalysis and organic chemistry. Hence, individuals who embark on this collaborative project will be prepared to their future career in an optimal manner. Importantly, the training will include a 3-month placement at one of the industry partners.

The position is available for the 21/09/17 and must be filled by the 01/06/17. Although the application deadline is set at the end of April, applications by the end of March are strongly encouraged. Informal contacts with Dr Aissa are also encouraged.