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  Using nutrigenetic, nutrigenomic and machine learning approaches to investigate the risk of cardiometabolic disease-related traits in ethnically diverse populations.


   Department of Food and Nutritional Sciences

   Applications accepted all year round  Self-Funded PhD Students Only

About the Project

This PhD project represents an exciting opportunity to develop and conduct research at the forefront of nutritional and genetic epidemiology, contributing to the prediction, prevention, and better understanding of the development of non-communicable diseases such as obesity and diabetes, using datasets from multiple ethnic groups. We are seeking a highly motivated candidate for a PhD project that will focus on nutritional genomics and statistical genetics. The project will focus on identifying genetic determinants of cardiometabolic traits and investigating the effect of these genetic determinants and lifestyle factors on these traits in multiple ethnic groups using detailed epidemiological analyses and machine learning approaches.

The student will use cutting-edge genetic epidemiological methods to investigate gene-diet interactions in ethnically diverse populations – both across the UK and across multiple global settings. Specific emphasis will be placed on the development of novel analytical approaches to the analysis of hypotheses related to gene-diet interactions. The student will receive training in nutrigenetics, nutrigenomics, genetic epidemiology, statistical genetics and bioinformatics. The student will also have the opportunity to discuss the exact title and nature of the project to suit their interests and to incorporate recent advances in these exciting areas.

This project provides an opportunity to work with a group that has a strong track record in nutritional and genetic epidemiology and to develop links with experts nationally and internationally. The successful candidate will be expected to actively participate in group meetings such as journal clubs and department seminars.

The project will be carried out at the Hugh Sinclair Unit of Human Nutrition, University of Reading, UK. The project will be supervised by Prof Vimal Karani, Professor in Nutrigenetics and Nutrigenomics. For an informal discussion, contact Prof Vimal Karani S (). 


Biological Sciences (4) Computer Science (8) Mathematics (25) Medicine (26) Sport & Exercise Science (33)

Funding Notes

BSc (grade 2:1 or 1) or MSc (merit or distinction) in a relevant subject

References

https://pubmed.ncbi.nlm.nih.gov/?term=vimaleswaran+ks&sort=date

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