About the Project
Over 15,000 patients per year in the UK undergo major chest (non-cardiac) or abdominal surgery. Lung complications such as atelectasis or infection following surgery occur in up 15 % of these patients and are linked to increased risk of death, increased likelihood of admission into an intensive care unit and a longer stay in hospital. Avoidance of these complications offers great benefits to patients and the NHS.
Enhanced recovery programmes are used in many types of non-lung surgery, e.g. bowel, uterus, orthopaedic and prostate. They lead to reduced complications and length of hospital stay. No such validated recovery programme exists for lung surgery. The principle to minimise the stress response after surgery by ensuring the patient is in the best possible condition for surgery , undergoes the best possible management during surgery and has the best possible post-operative rehabilitation.
Active areas of research for our group in this field are smoking cessation and e-cigarettes , carbohydrate loading, peri-operative nutrition , pre and post-operative pulmonary rehabilitation specifically delivery through smart technology, physiotherapy interventions, analgesia technique, minimally invasive surgery , prediction of short and long post-operative morbidity through assessment of regional ventilation by CT and chest wall motion analysis following surgery.
Person Specification
Applicants should have a strong background in clinical research, and ideally a background in surgery. They should have a commitment to research in surgery or anaesthesia or respiratory medicine and hold or realistically expect to obtain at least an Upper Second Class Honours Degree in a relevant subject.
How to apply
Informal enquiries should be directed to [Email Address Removed]
To apply, please send the following to Mr Naidu [Email Address Removed]:
• A detailed CV, including your nationality and country of birth;
• Names and addresses of two referees;
• A covering letter highlighting your research experience/capabilities;
• Copies of your degree certificates with transcripts;
• Evidence of your proficiency in the English language, if applicable.
References
1. Yeung J, Melody T, Kerr A, Naidu B, Middleton L, Tryposkiadis K, Daniels J, Gao F; TOPIC Study Investigators.. Randomised controlled pilot study to investigate the effectiveness of thoracic epidural and paravertebral blockade in reducing chronic post-thoracotomy pain: TOPIC feasibility study protocol. BMJ Open. 2016 Dec 1;6(12):e012735. doi: 10.1136/bmjopen-2016-012735. PubMed PMID: 27909035; PubMed Central PMCID: PMC5168654.
2. Elshafie G, Kumar P, Motamedi-Fakhr S, Iles R, Wilson RC, Naidu B. Measuring changes in chest wall motion after lung resection using structured light plethysmography: a feasibility study. nteract Cardiovasc Thorac Surg. 2016 Jun 16. pii: ivw185. [Epub ahead of print] PubMed PMID: 27316661.
3. Lugg ST, Agostini PJ, Tikka T, Kerr A, Adams K, Bishay E, Kalkat MS, Steyn RS, Rajesh PB, Thickett DR, Naidu B. Long-term impact of developing a postoperative pulmonary complication after lung surgery. Thorax. 2016 Feb;71(2):171-6. #
4. Farley A, Aveyard P, Kerr A, Naidu B, Dowswell G. Surgical lung cancer patients' views about smoking and support to quit after diagnosis: a qualitative study. J Cancer Surviv. 2015 Aug 23. [Epub ahead of print] PubMed PMID: 26298019.
5. Agostini PJ, Naidu B, Rajesh P, Steyn R, Bishay E, Kalkat M, Singh S. Potentially modifiable factors contribute to limitation in physical activity following thoracotomy and lung resection: a prospective observational study. J Cardiothorac Surg. 2014 Sep 27;9:128. doi: 0.1186/1749-8090-9-128. PubMed PMID: 25262229.
6. Bradley A, Marshall A, Stonehewer L, Reaper L, Parker K, Bevan-Smith E, Jordan C, Gillies J, Agostini P, Bishay E, Kalkat M, Steyn R, Rajesh P, Dunn J, Naidu B. Pulmonary rehabilitation programme for patients undergoing curative lung cancersurgery. Eur J Cardiothorac Surg. 2013 Oct;44(4):e266-71.
7. Yeung JH, Gates S, Naidu BV, Wilson MJ, Gao Smith F. Paravertebral block versus thoracic epidural for patients undergoing thoracotomy. Cochrane Database Syst Rev. 2016 Feb 21;2:CD009121. doi: 10.1002/14651858.CD009121.pub2. Review. PubMed PMID: 26897642.
8. Agostini P, Naidu B, Cieslik H, Steyn R, Rajesh PB, Bishay E, Kalkat MS, Singh S. Effectiveness of incentive spirometry in patients following thoracotomy and lung resection including those at high risk for developing pulmonary complications. Thorax. 2013 Feb 21. doi: 10.1136/thoraxjnl-2012-202785. [Epub ahead of print] PubMed PMID: 23429831.
9. Agostini P, Cieslik H, Bishay E, Kalkat MS, Rajesh PB, Steyn RS, Naidu B The impact and risk factors for Post operative Pulmonary Complications following Lung Resection in current UK practice – Are there any modifiable factors?” Thorax. 2010 Sep;65(9):815-8.
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