The synthesis and application of novel heterocycles for bacterial detection (Advert Ref: RDFC17/APP/STANFORTH)

This project will extend a well-established research theme within the Stanforth group aimed at synthesising novel heterocyclic enzymatic substrates for the detection and identification of clinically important bacteria. The reaction of bacterial enzymes with the heterocyclic substrates will produce fluorescent or coloured heterocyclic products, thus enabling the detection of bacteria. The profile of enzymatic activity allows the identification of bacterial species. This is extremely important in health-care sector (particularly in hospitals) and other areas, eg environmental monitoring, food quality assurance. We have several on-going projects and the student attached to this project will take over the development of the most promising areas. The project will involve mainly organic synthesis in order to prepare the substrates and some microbiology (training will be given) for the evaluation of the substrates.

Eligibility and How to Apply:
Please note eligibility requirement:
• Academic excellence of the proposed student i.e. 2:1 (or equivalent GPA from non-UK universities [preference for 1st class honours]); or a Masters (preference for Merit or above); or APEL evidence of substantial practitioner achievement.
• Appropriate IELTS score, if required.

For further details of how to apply, entry requirements and the application form, see
https://www.northumbria.ac.uk/research/postgraduate-research-degrees/how-to-apply/

Please ensure you quote the advert reference above on your application form.

Start Date: 2 October 2017

Northumbria University is an equal opportunities provider and in welcoming applications for studentships from all sectors of the community we strongly encourage applications from women and under-represented groups.