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  Molecular and cellular basis of cell competition


   Albert Einstein College of Medicine

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  Prof Nicholas Baker  No more applications being accepted  Funded PhD Project (Students Worldwide)

About the Project

Cell competition recognizes and eliminates abnormal cells during development and is thought to occur in aging and in cancer (Curr Opin Cell Biol 48:40-46 2017; Curr Opin Cell Biol 48:106-112 2017). Our group has used genetic screens in Drosophila to identify genes involved in cell competition. A PhD position is available to participate in the characterization of these genes and their roles at the molecular and cellular levels. The successful candidate will employ genetic, molecular genetic, and biochemical approaches to identify and characterize mechanisms that recognize and eliminate cells with imbalances in ribosomal proteins, and the physiological significance of cell competition in vivo. The specific experiments may include biochemical, genetic, or live imaging approaches.

An application to the PhD program in Biomedical Sciences at Albert Einstein College of Medicine will also be required. More details are available at http://www.einstein.yu.edu/education/phd/prospective-students/admissions.aspx.
The deadline for online submission of all materials is December 11, 2017. Applicants interested in the project should make contact with Prof. Baker directly as soon as possible and before 27 November 2017.

Albert Einstein College of Medicine is a premier, research-intensive medical school dedicated to innovative biomedical investigation and to the development of ethical and compassionate physicians and scientists. Inspired by the words of our namesake, we welcome students, faculty and staff from diverse backgrounds who strive to enhance human health in the community and beyond.
Graduate students will be eligible for university housing as well as stipend and tuition waiver.

The Albert Einstein College of Medicine is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

References

Baker, N.E. (2017) Mechanisms of cell competition emerging from Drosophila studies. Curr Opin Cell Biol 48:40-46.
Maruyama, T. and Fujita, Y. (2017) Cell competition in mammals - a novel homeostatic machinery for embryonic development and cancer prevention. Curr Opin Cell Biol 48:106-112.

 About the Project