1 PhD Student Position in the field of Immunology/ Biochemistry funded by the Austrian Science Fund (FWF): determining novel pathways of T cell regulation

T cells are important players in the onset of a specific immune response, tailor the defense against pathogens that escaped the first line of immune protection and actively participate in the formation of a correct immunological memory. They can however also lead to allergy or autoimmune diseases if they are improperly regulated. Therefore, factors and pathways that shape T cell responses are important to study in order to find targets for immune modulation.

The project: The FWF-funded project focuses on studies to determine how T cells are regulated by a recently identified novel guanine nucleotide exchange factor using a combination of cellular experiments, genetic mouse models and biochemical/proteomics approaches.

The Research Groups: The PhD student will be embedded in a highly multidisciplinary and collaborative research environment at the Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology. In addition, the PhD students will benefit from the close proximity of the Vienna General Hospital (AKH), as parts of the projects also involve collaborations with clinical departments.

The project will be under the supervision of Ruth Herbst. Details about the host laboratories can be found at:
Ruth Herbst: https://cluster.meduniwien.ac.at/index.php?id=11256

The Candidate: The Applicant should hold a master’s degree in molecular biology, biochemistry, or a related discipline and have documented experience in molecular biology and mammalian cell culture methods. Previous experience with cloning, transfection, immunoblot assays, immunocytochemistry, immunological assays, primary cell cultures and/or flow cytometry is advantageous.

We are looking for highly motivated students who are enthusiastic about working on fundamental biological questions with applications to important clinical problems. You should be a critical scientist with a creative mind and a team player with proficient communication skills.

Please send applications (including CV, a letter of intent and contact information of at least two referees) as a single pdf to the address below. Informal enquiries are welcome.

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