ALDH enzymes in melanoma stem cell lineages at University of Edinburgh on FindAPhD.com

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Dr E Patton No more applications being accepted Competition Funded PhD Project (European/UK Students Only)

About the Project

ALDH enzymes are aldehyde detoxifying enzymes that are expressed in somatic and cancer stem cell lineages. We are using the zebrafish model system to study the role of ALDH enzymes in the melanocyte stem cell and in melanoma stem cell populations in cancer progression, regression and recurrence. The Aim of this PhD project is to identify the ALDH enyzmes in melanoma stem cells, and use genetics and live-imaging to determine their function and expression patterns in melanoma progression, and in response to drug treatment. Ultimately, we aim to target these subpopulations and determine the effect on disease outcome.

This project is part of an MRC four-year PhD programme in Human Genetics, Genomics and Disease, at the MRC Human Genetics Unit, University of Edinburgh. See website for details of other projects.

Further information about the programme and details of how to apply please visit www.ed.ac.uk/mrc-human-genetics-unit/study-with-us

Funding Notes

Applicants should hold at least an upper second-class degree in a relevant subject and comply with English language requirements. For full funding students must be UK or EU citizens who have been resident in the UK for 3 years prior to commencement.The studentship offers a stipend of £17,500 per annum.

Where will I study?

University of Edinburgh

One of the world''s top universities, consistently ranked in the world top 50 and placed 20th in the QS World University Rankings 2020. We provide a stimulating working, learning and teaching environment with access to excellent facilities and attract the world''s best, from Nobel Prize winning laureates to future explorers, pioneers and inventors.

ALDH enzymes in melanoma stem cell lineages

University of Edinburgh College of Medicine and Veterinary Medicine

This project is no longer listed on FindAPhD.com and may not be available.

About the Project

Funding Notes

Where will I study?

University of Edinburgh

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