Using Real-World Data and Decision-Analytic Modelling to Inform a Target Product Profile for a Novel Rapid Point-of-Care Test for Clostridium difficile Infection

This project is offered as part of the Medical Research Foundation National PhD Training Programme in AMR: https://www.findaphd.com/search/PhDDetails.aspx?CAID=3755

When new clinical diagnostics tests are developed, the economic evaluation to determine cost-effectiveness is traditionally carried out at the point when the technical development phases are complete and the diagnostic test has been fully evaluated in clinical practice. The lengthy and expensive nature of the evidence generation required has resulted in long delays in getting a test from bench to bedside, causing a high attrition of diagnostic companies, and very few novel diagnostics are actually deployed into clinical practice. A large consortium of researchers at the University of Leeds is developing a rapid point-ofcare test for Clostridium difficile infection (CDI). In this PhD project, you will work with laboratory scientists and analyse routine health data to develop an early economic model to
define the characteristics of the new test required for it to be clinically- and cost-effective. This project will facilitate the development of strong economic modelling skills, experience in analysing routinely-collected healthcare data, and exposure to the laboratory validation of novel in-vitro diagnostic tests. The successful candidate will be embedded in the MRC Doctoral Training Partnership, Faculty of Medicine and Health, University of Leeds which will provide additional training opportunities and local student cohort activities.

Apply here: http://www.leeds.ac.uk/info/130206/applying/91/applying_for_research_degrees

When completing the application form please select programme code “php-elec-ft” and include Medical Research Foundation National PhD Training Programme in AMR Research, the project title, the name of the lead supervisor in section K. We also require 2 academic references to support your application. Please ask your referees to send these references on your behalf, directly to [Email Address Removed] by no later than the deadline. Any queries regarding the project or the application process should be directed to [Email Address Removed].