Dr D Player
No more applications being accepted
Funded PhD Project (European/UK Students Only)
About the Project
Peripheral nerve damage can occur as a result of a spectrum of traumatic injuries, leading to partial or complete denervation of target skeletal muscles. Patients with peripheral nerve injury (PNI) often suffer from poor functional recovery following nerve regeneration, either naturally or following surgical intervention.
The cellular and molecular mechanisms that regulate skeletal muscle innervation (motor unit remodeling, synapse formation and stabilization etc.) following injury are vastly complex, and recapitulate many of the mechanisms that are required during development and early post-natal maturation. However, the role of skeletal muscle regeneration (satellite cell activation and differentiation) in nerve regeneration and reinnervation following injury, is yet to be fully understood. Particularly, the cellular and molecular mechanisms regulating communication between skeletal muscle and neural tissue, have not been fully characterised.
There is an identified clinical need to explore this area further, to determine whether there may be suitable interventions to maximise functional recovery following PNI. This will be achieved through the use of in vivo and in vitro methodologies.
Person Specification
Essential
Applicants are expected to have obtained at least an upper second-class honours degree (2:1, or equivalent qualification) in a relevant subject. This may include; biomedical science, biochemistry, physiology and cell and molecular biology.
The English language level for this programme is standard ( GCSE/IGCSE pass at grade C or 5), please see the following link for more information: UCL's English Language Requirement Page.
Desired
Qualification to Master’s level (MSc, or equivalent), or practical experience in a suitable subject would be an advantage, although is not essential. The candidate would also be expected to show an interest in muscle physiology and translational medicine.
Application
To make an application, please email your CV and a covering letter to: Dr Darren Player ([Email Address Removed]) explaining your interest in the project, research experience (including examples of previous project work) and why you would be a suitable PhD candidate.
Closing date: 12th March 2018
Interview date: 19th March 2018
Intended Studentship start date: 1st June 2018
Funding Notes
Based at the UCL Institute of Orthopaedics and Musculoskeletal Science (Division of Surgery and Interventional Science), Royal National Orthopaedic Hospital, you will have the opportunity to work with leading academics and clinicians this field. There will also be an opportunity to work across the Division’s other campuses; Royal Free Hospital and Bloomsbury (Charles Bell House).
Funding for the PhD studentship comes from the Professor John Scales Scholarship Award.
£16,777 per annum plus UK/EU tuition fees [dependent on the registration date of the student]
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