Enzyme Engineering for Industrial Biocatalysis

Fossil fuels have long been the primary energy and carbon sources, providing the raw materials needed for the manufacture of a wide range of products that we use daily. Challenged by the risks of CO2 emission and depleting fossil resources, we are in desperate need of more sustainable and environmentally friendly solutions. Industrial biotechnology is changing how we manufacture chemicals, materials, fuels and energy. Enzymes lie at the core of industrial biotechnology and our group has been working closely with industrial partners to screen and develop new enzymatic processes. With a specific focus on hydrolases, this project involves engineering enzymes and developing bioprocess suitable for industrial-scale biocatalysis.

The student will join the multi-disciplinary ChELSI institute and the newly established Advanced Biomanufacturing Centre (ABC) at the University of Sheffield, which is equipped with state-of-the-art research facilities. He/she will receive a broad training in molecular biology, protein engineering, synthetic biology, biophysics and chemical engineering. Further, he/she will engage with the Doctoral Development Programme designed to help developing specialist and transferable skills, which will enhance students’ research capability and employability.