Dr P Skipp
No more applications being accepted
Funded PhD Project (European/UK Students Only)
About the Project
Allergies to small organic chemicals are a public health concern and can manifest themselves in a variety of clinical outcomes. For example, allergic contact dermatitis (ACD) is a T-cell mediated, delayed hypersensitivity that typically results in skin symptoms, which can be severe but not life-threatening. By contrast, chemical respiratory and drug allergies can be IgE-mediated and potentially fatal. What drives the subsequent divergent immunological outcomes i.e. the differences in the main effector responses associated with skin and respiratory sensitisation is unknown.
In collaboration with Unilever PLC, this research project capitalises on novel proteomic techniques recently developed at the UoS to characterise both the proteins modified and the MHC peptide antigens presented after sensitiser exposure. This programme of research presents an exciting opportunity to investigate and elucidate the differences in effector responses between skin and respiratory sensitisation at the molecular level. Working within a research team based within the Centre for Proteomic Research, the successful student will develop expertise in using the latest techniques in proteomics, immunopeptidome analysis and bioinformatics.
Funding Notes
The project is funded for 3 years and welcomes applicants from the UK and EU who have or expect to obtain at least an upper second class degree or students recently completing a Master’s degree in Biological Sciences or allied subjects. Funding will cover fees and an enhanced annual stipend.
Due to funding restrictions this position is only open to UK/EU applicants.
References
Applications for an MPhil/PhD in Biological Sciences should be submitted online at:
https://studentrecords.soton.ac.uk/BNNRPROD/bzsksrch.P_Login?pos=4973&majr=4973&term=201819 Please place Dr Paul Skipp name in the field for proposed supervisor.
General enquiries should be made to Dr Paul Skipp at:
pjss@soton.ac.uk. Any queries on the application process should be made to fels-pgr-apply@soton.ac.uk
Applications will be considered in the order that they are received, and the position will be considered filled when a suitable candidate has been identified.
The University of Southampton and Biological Sciences both hold an Athena Swan Silver Award, respectively, demonstrating their commitment to provide equal opportunities and to advance the representation of women in STEM/M subjects: science, technology, engineering, mathematics and medicine. Due consideration will be given to applicants who have taken a career break. University benefits include onsite childcare facilities, state-of-the-art on-campus sports, arts and culture facilities, a full programme of events and a range of staff discounts.
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