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We have 64 Biological Sciences PhD Research Projects PhD Projects, Programmes & Scholarships in Liverpool

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Biological Sciences PhD Research Projects PhD Projects, Programmes & Scholarships in Liverpool

We have 64 Biological Sciences PhD Research Projects PhD Projects, Programmes & Scholarships in Liverpool

University of Liverpool

We are curious problem solvers at the forefront of world-leading research. A hotbed of discovery and innovation, we're committed to addressing some of the toughest challenges in our society, both now and in the future. Join us in the search for answers by pursuing your PhD at the Original Redbrick.

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Study of early pathological changes in calcified cartilage in osteoarthritis and alkaptonuria

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
We are seeking a motivated individual to work on this exciting project investigating the role that the calcified cartilage has in rare and common joint osteoarthritis, using novel approaches such as gene silencing and establishment of a 3D chondrocyte cell culture model. Read more
 Supervisor: Dr JH Hughes
 10 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Development of novel therapies for Hirschsprung’s Disease

University of Liverpool Faculty of Health and Life Science
As a PhD student, you'll be part of a groundbreaking project aiming to revolutionise the treatment landscape for Hirschsprung's Disease (HSCR). Read more
 Supervisors: Miss RH Harwood, Dr B Wilm, Miss SA Almond
 26 April 2024  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Gaining mechanistic insights into Atrial Fibrillation: Bench to bedside approaches

University of Liverpool Department of Pharmacology and Therapeutics
Atrial fibrillation (AF) is a common arrhythmia with symptoms like irregular heart rate, palpitations, shortness of breath, tiredness, and dizziness. Read more
 Supervisor: Dr RB Burton
 1 July 2024  PhD Research Project  Self-Funded PhD Students Only
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Understanding immune recognition in oral premalignant disorders (OPMDs)

University of Liverpool Department of Cellular and Molecular Physiology
Oral potentially malignant disorders (OPMD) are associated with an increased risk of transformation to oral squamous cell carcinoma (OSCC). Read more
 Supervisors: Prof K Hunter, Prof NS Savelyeva, Prof C Ottensmeier, Prof RS Shaw
 26 April 2024  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Creation of cell lines modelling complex karyotype in B cell lymphomas using CRISPR/Cas9

University of Liverpool Institute of Systems, Molecular and Integrative Biology
Chronic lymphocytic leukaemia (CLL) and diffuse large B cell lymphoma (DLBCL) make up more than half of all the newly diagnosed cases of non-Hodgkin’s lymphoma (NHL), the 6th most common cancer in the UK. Read more
 Supervisors: Dr J Slupsky, Dr N Kalakonda, Dr M Glenn
 1 May 2024  PhD Research Project  Self-Funded PhD Students Only
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Preclinical testing of collagen synthesis inhibitors for fibrotic disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more
 Supervisor: Dr EG Laird
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Elucidation of a new pathological mechanism for brittle bone disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
The incidence of the brittle bone disease osteogenesis imperfecta (OI) is estimated to be around 1 in 10,000 individuals. The phenotypic spectrum of OI ranges from mild to perinatal lethal and includes extra-skeletal connective tissue manifestations. Read more
 Supervisor: Dr EG Laird
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Alterations in reparative dentinogenesis with ageing, gender and genetic predisposition

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology
Dental pulp exposure caused by tooth decay or injury can lead to life-threatening infections. Following injury, reparative dentinogenesis serves a vital purpose through the accelerated generation of tertiary dentine, comprising mineral and type I collagen. Read more
 Supervisors: Dr EG Laird, Dr N Longridge, Prof FJ Jarad
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the regulation of neutrophil gene expression by intracellular signalling and small non-coding RNAs

University of Liverpool Institute of Life Course and Medical Sciences
Immune-mediated inflammatory diseases (IMID) such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) affect millions of people worldwide and cause debilitating and disabling musculoskeletal disease. Read more
 Supervisors: Dr HL Wright, Prof MJ Peffers
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of neutrophil-mediated tissue damage in a model of lupus nephritis

University of Liverpool Institute of Life Course and Medical Sciences
Systemic lupus erythematosus (SLE) is a rare autoimmune disease that affects around 5 million people worldwide. It disproportionately affects women and is incurable. Read more
 Supervisors: Dr HL Wright, Dr D Wilkinson, Dr D Turner
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Using pre-clinical models of disease to define new targets to slow joint degeneration in osteoarthritis

University of Liverpool Institute of Life Course and Medical Sciences
The main overall aim of this project is to understand mechanisms of joint degeneration during osteoarthritis progression in order to define new targets for therapy. Read more
 Supervisor: Dr B Poulet
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of Aquaporins in age related diseases

University of Liverpool Institute of Life Course and Medical Sciences
Physical frailty, with its associated immobility and disability, is a major factor limiting independence among older people. A key contributor to frailty is a decline in muscle mass and strength (sarcopenia) and the burden of sarcopenia is substantial, with a cost to the NHS of ~£2.5bn/pa. Read more
 Supervisor: Dr C Staunton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Control of bone shape and function by the extracellular matrix Fibrillin-1

University of Liverpool Institute of Life Course and Medical Sciences
Bones are tightly regulated structures that remodel their structure to adapt to changes in their mechanical environment. With ageing, this mechanical response is often dampened, leading to bone loss and weakness. Read more
 Supervisor: Dr B Poulet
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Uncovering the mechanochemical signalling inputs that drive gastruloid axial patterning

University of Liverpool Institute of Life Course and Medical Sciences
How the early mammalian embryo converts a mass of identical cells in an organism with multiple axes of symmetry (anteroposterior, dorsoventral, mediolateral) is a critical question in developmental biology. Read more
 Supervisor: Dr D Turner
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of oxidative metabolites in joint destruction in osteoarthritis

University of Liverpool Institute of Life Course and Medical Sciences
We are seeking a motivated researcher to work on a pioneering project investigating the role of oxidative stress in alkaptonuria (AKU) and associated conditions. Read more
 Supervisors: Dr BN Norman, Dr JH Hughes, Prof G Bou-Gharios
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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