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We have 74 Biological Sciences PhD Projects, Programmes & Scholarships in Sheffield

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Biological Sciences PhD Projects, Programmes & Scholarships in Sheffield

We have 74 Biological Sciences PhD Projects, Programmes & Scholarships in Sheffield

Sheffield Hallam University

Research that transforms lives

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University of Sheffield

Our University has a reputation for world-class teaching and research excellence across a variety of disciplines

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Engineering Virus-Like Particles for Next-Generation Vaccine Manufacturing

University of Sheffield Department of Chemical & Biological Engineering
Virus-like particles (VLPs) are structures typically composed of viral structural proteins that self-assemble into virus-like structures. Read more
 Supervisors: Dr K Tee, Prof TS Wong, Dr C Evans
 30 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Microbial Community Dynamics and Biocide Susceptibility Profiles in Chronic Wound Biofilms

Sheffield Hallam University Biomolecular Sciences Research Centre
The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more
 Supervisors: Dr S Forbes, Dr KM Miller, Dr N Aberdein, Dr F Clegg
 10 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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The role of eIF2Bα in the response to Integrated Stress Response (ISR) modulation in cancer

Sheffield Hallam University Biomolecular Sciences Research Centre
The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more
 Supervisors: Dr E Allen, Dr SC Campbell
 10 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Untangling how Shelterin safeguards telomere structure and stability - one molecule at a time

University of Sheffield School of Biosciences
Background. Telomeres solve two problems with linear chromosomes. the end-replication problem, DNA loss from the end of chromosomes every replication cycle; and the end-protection problem, protection of the chromosome ends to prevent chromosome fusions. Read more
 Supervisors: Dr M Newton, Dr A Pyne
 3 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Fully-funded EPSRC Centre for Doctoral Training in Green Industrial Futures

University of Sheffield
Our four year doctoral programme challenges our students to work on cutting-edge, innovative research projects that will address key challenges faced by industrial stakeholders. Read more
 Funded PhD Programme (Students Worldwide)  EPSRC Centre for Doctoral Training
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How does glycolysis influence the oral environment during caries and periodontitis?

University of Sheffield School of Clinical Dentistry
Glycolysis plays a pivotal role during energy metabolism and cellular responses in oral health and pathology. It is a crucial metabolic pathway for energy production, especially in inflammation or infection scenario, that is essential for maintaining tissue integrity and function in the gingiva and dental pulp. Read more
 Supervisors: Dr C M Neves, Prof G Stafford
 31 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Targeting dormant cancer cells in myeloma

University of Sheffield School of Medicine and Population Health
Multiple myeloma is the second most common blood cancer and remains essentially incurable. Chemotherapy is effective at reducing tumour and extends survival, but it never fully eradicates disease, so patients face inevitable relapse. Read more
 Supervisors: Dr A Green, Prof S El-Khamisy
 31 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Unravelling the role of P4HB in skeletal development: towards treatment of heritable bone fragility

University of Sheffield School of Medicine and Population Health
Osteogenesis Imperfecta (OI) affects 1 in 15-20,000 live births and results in a childhood with frequent fractures, reduced mobility and joint problems. Read more
 Supervisor: Dr M Balasubramanian
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Precision Therapy for NBAS-related disorder

University of Sheffield School of Medicine and Population Health
It is very well recognised that rare diseases offer the potential to uncover new information about mechanisms underlying a range of phenotypes. Read more
 Supervisor: Dr M Balasubramanian
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Mining data from National genomics Research Library to enable new gene discovery

University of Sheffield School of Medicine and Population Health
Whole Genome Sequencing (WGS) is a new genomic testing technology and process which became available through the NHS in April 2022. Read more
 Supervisor: Dr M Balasubramanian
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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How are mass extinctions shaping biodiversity?

University of Sheffield School of Biosciences
Background. Understanding the effects of mass extinctions on life on Earth is of crucial importance in the context of the current biodiversity crisis. Read more
 Supervisors: Dr T Guillerme, Dr G Thomas
 22 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Characterising vegan cheese: Its microstructure and the influence of ingredients and process

Sheffield Hallam University Materials and Engineering Research Institute
The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more
 Supervisors: Dr C Millman, Dr SC Campbell, Dr RG Gillis
 10 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Mathematical and Computational Modelling of Haemodynamics for Cerebral Aneurysm Progression

Sheffield Hallam University Materials and Engineering Research Institute
The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more
 Supervisors: Dr JS Spendlove, Prof AS Shenfield, Dr XX Xu, Prof I Halliday
 10 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Blue Spaces in Urban Places: Lipidomics Underpinning Community Empowerment

Sheffield Hallam University Biomolecular Sciences Research Centre
The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more
 Supervisors: Dr R Schwartz-Narbonne, Dr ML Lacey, Dr R Sharpe
 10 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Diabetes and Breast Cancer from the perspective of oestrogen receptor expression

Sheffield Hallam University Biomolecular Sciences Research Centre
The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more
 Supervisors: Dr SA Ahmed, Dr NP Peake, Dr DK Kelly
 10 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Unlocking Precision Medicine: Advanced Survival Analysis Tools for Cancer Biomarker Validation

Sheffield Hallam University Computing and Informatics
The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more
 Supervisors: Dr LQ Quayle, Dr KH Harris, Dr NC Cross
 10 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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What do effect sizes mean in real terms? Benchmarking effect sizes in behavioural research

University of Sheffield Department of Psychology
A fully-funded studentship is available to work alongside the team working on the BR-UK project (https://www.linkedin.com/company/behavioural-research-uk/) at the University of Sheffield. Read more
 Supervisors: Dr H Baird, Prof T Webb
 24 April 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Using genome sequencing to find the cause of undiagnosed rare conditions affecting bowel, heart, lung or brain in adults

University of Sheffield School of Medicine and Population Health
In the UK, a rare condition is one that affects fewer than 1/2000 people. Around 70% of rare conditions have a genetic cause (ie are caused by a change… Read more
 Supervisor: Dr A McNeill
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Sheffield Hallam Opportunity PhD Scholarships

Sheffield Hallam University
Sheffield Hallam is committed to addressing barriers to higher education for under-represented groups. To help address underrepresentation in our postgraduate research student community, we are offering the below scholarships for academic year 2024/25. Read more
 Funded PhD Programme (UK Students Only)  4 Year PhD Programme
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Role of primary cilia in skeletal muscle stem cells and muscle regeneration

University of Sheffield School of Biosciences
Primary cilia are cellular organelles present at the surface of many cell types in vertebrates. In recent years, they have been shown to play essential roles in relaying signalling information from the environment to the cell. Read more
 Supervisor: Dr A G Borycki
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Control of skeletal muscle regeneration and aging by cell signalling

University of Sheffield School of Biosciences
The ability of skeletal muscles to regenerate in response to injury, exercise, growth or disease depends on a population of adult skeletal muscle stem cells. Read more
 Supervisor: Dr A G Borycki
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genomic and Proteomics-Based Characterisation of Microalgal Cell Factories

University of Sheffield Department of Chemical & Biological Engineering
Microalgae have generated increasing interest as microbial cell factories to produce proteins, pigments, therapeutics, and nutraceuticals. Read more
 Supervisors: Dr J Pandhal, Prof MJ Dickman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Glycosylation in Microalgal Host Cells

University of Sheffield Department of Chemical & Biological Engineering
Microalgae have generated increasing interest as microbial cell factories to produce therapeutics proteins. This is because they can grow on very cheap media and their GRAS (generally regarded as safe) status means they are a fantastic option for the production of therapeutics that can be administered orally. Read more
 Supervisors: Dr J Pandhal, Dr C Evans
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Henry Royce Institute PhD Opportunities

University of Sheffield
Right now, our society faces huge, urgent challenges. From the imperative to achieve net-zero, to the need to build a resilient, circular economy in an uncertain world, to the drive for increased productivity as our fellow nations embrace the digital revolution. Read more
 Funded PhD Programme (Students Worldwide)  ESRC Centre for Doctoral Training
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The identification of allosteric inhibitors of high value therapeutic targets

University of Sheffield School of Biosciences
This study will develop a novel approach to identify allosteric inhibitor sites on a wide variety of high-value therapeutic targets, including protein kinases, protein phosphatases and small G-proteins. Read more
 Supervisor: Prof J P Waltho
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of a Long Acting Parathyroid Hormone Fusion for the Treatment of Hypoparathyroidism

University of Sheffield School of Medicine and Population Health
Background. Parathyroid hormone (PTH) is an 84 aa peptide produced by the parathyroid glands and is responsible for calcium homeostasis. Read more
 Supervisors: Dr I Wilkinson, Prof J Newell-Price
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Finding the cause of familial facial (Bell’s) palsy

University of Sheffield School of Medicine and Population Health
The facial (VII) cranial nerve controls the muscles of facial expression, supplies taste sensation to parts of the tongue and controls a small muscle connected to the ear drum. Bell’s palsy is the clinical condition in which there is impaired function of the facial nerve, associated with facial muscle weakness. Read more
 Supervisor: Dr A McNeill
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring Uncharted Territories: Investigating the Impact of Follicular Fluid Extracellular Vesicles on Spermatozoa Function

University of Sheffield School of Medicine and Population Health
The intricate dynamics underlying successful mammalian reproduction continue to captivate scientific inquiry. However, the mechanisms governing the interaction between spermatozoa and the female reproductive tract remain elusive. Read more
 Supervisor: Prof A Fazeli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Deconvoluting the spatial multi-omic landscape of high-grade glioma to target post-surgical residual disease

University of Sheffield School of Medicine and Population Health
Background. High-grade gliomas are the most common cancers arising within the brain and contribute to ~190,000 brain tumour related deaths/year globally. Read more
 Supervisors: Dr S Collis, Dr O Rominiyi, Dr M Dunning
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Effect of androgens on preantral follicle development

University of Sheffield School of Medicine and Population Health
Polycystic ovary syndrome (PCOS) is a condition that affects >5% of women of reproductive age and is the most common cause of menstrual dysfunction and is associated with metabolic abnormalities and increased risk to long-term health. Read more
 Supervisors: Dr M Fenwick, Dr N Krone
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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