Biological Sciences PhD Research Projects PhD Projects, Programmes & Scholarships in Bradford

We have 128 Biological Sciences PhD Research Projects PhD Projects, Programmes & Scholarships in Bradford

Integrated omics approach to psychiatric disorders

University of Bradford Faculty of Life Sciences

Research Group: Chemistry and Biosciences

In psychiatry, the selection of antipsychotics and antidepressants is led by a trial-and-error approach. The prescribing of these medications is complicated by sub-optimal efficacy and high rates of adverse drug reactions (ADRs). Read more

Supervisors: Prof K Poterlowicz, Dr S McLean

Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic reprogramming of immune cells; novel mechanism for drug resistance in leukaemia

University of Leeds Faculty of Medicine and Health

Under pathogenic challenges, cells of the haematopoietic system become epigenetically reprogrammed and establish immune memory. Read more

Supervisor: Dr P Laslo

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

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Oncology: Evaluating Photodynamic Therapy in colorectal cancer using patient-derived organoids

University of Leeds Faculty of Medicine and Health

Colorectal cancer (CRC) is the 3rd most common cancer worldwide. Surgery is first line treatment and often in adjunct with chemotherapy. Read more

Supervisors: Dr I Knot, Prof D Jayne

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

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Translational Medicine: Understanding the mechanism(s) of resistance to EPA to personalise therapy and improve outcome

University of Leeds Faculty of Medicine and Health

Advanced colorectal cancer (CRC) is the UK’s second most lethal cancer, with limited treatment options for unresectable metastatic tumours. Read more

Supervisors: Dr MA Volpato, Prof M Hull

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer Biology: The role of Wnt signaling in glioblastoma therapeutic resistance

University of Leeds Faculty of Medicine and Health

Glioblastoma is a deadly brain tumour treated with surgery, radiotherapy and chemotherapy with patient survival of 6-15 months. Read more

Supervisors: Dr G Mavria, Dr S Bell, Dr C Toomes

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

University of Leeds Faculty of Medicine and Health

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more

Supervisors: Dr F Errington-Mais, Dr V Jennings

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical: Adherence with Cancer Treatment in Adolescents and Young Adults

University of Leeds Faculty of Medicine and Health

Adherence with therapy is a significant clinical problem in young people, for many reasons. The scale of this has never been quantified in a population-based setting. Read more

Supervisors: Dr D Stark, Dr R Feltbower

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

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Genetics: Unravelling the Norrin/beta-catenin signaling pathway and its role in retinal angiogenesis and blindness

University of Leeds Faculty of Medicine and Health

Our previous work on the genetic analysis of individuals with the inherited retinal disease Familial Exudative Vitreoretinopathy (FEVR), has helped identify a new angiogenesis pathway, the Norrin/beta-catenin pathway. Read more

Supervisors: Dr C Toomes, Dr J Bond, Dr S Bell

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Complex 3D modelling of the tumour microenvironment for immunotherapy combination screening

University of Leeds Faculty of Medicine and Health

Cancer immunotherapy holds significant promise for the treatment of a range of cancers. Read more

Supervisors: Dr MA Volpato, Dr F Errington-Mais

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic mechanisms causing malignant transformation of B cells and plasma cells

University of Leeds Faculty of Medicine and Health

Cancers of B cells and plasma cells, lymphomas and multiple myeloma, can be very aggressive, and often the cancer rapidly reoccurs after standard therapy. Read more

Supervisor: Prof U Klein

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

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Virology: Unique Antiviral Therapy targeting Zika and Related Viruses

University of Leeds Faculty of Medicine and Health

Zika Virus (ZIKV) has emerged as a new mosquito-borne threat to public health after the devastating South American outbreak. Read more

Supervisors: Dr S Griffin, Dr A Kalli, Dr C McKimmie

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

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Virology: Sun exposure as a novel risk factor for Zika virus infection

University of Leeds Faculty of Medicine and Health

Mosquito-borne disease is now receiving unprecedented attention due to major outbreaks in new geographic areas including Brazil, Mexico, India, China, the Middle East and SE Asia. Read more

Supervisors: Dr C McKimmie, Dr K Shams, Dr S Griffin

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

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Immunotherapy: Manipulating T cell metabolism to improve anti-tumour immunity

University of Leeds Faculty of Medicine and Health

The induction of immune responses to tumours can provide long-lasting protection from cancer. In this regard, T cells can suppress tumour growth by directly killing cancer cells and by producing inflammatory cytokines. Read more

Supervisors: Dr M Lorger, Dr R Salmond

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

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Immunotherapy: Killing Cancer using Dead Virus

University of Leeds Faculty of Medicine and Health

It is now accepted that our immune systems can hold the key to treating otherwise incurable cancers. So-called “immunotherapy” is an increasingly common method of treating tumours, leading to impressive increases in patient responses. . Read more

Supervisors: Dr S Griffin, Dr A Samson

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

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Haematology: Oncogenic reprogramming of immune cells

University of Leeds Faculty of Medicine and Health

Under pathogenic challenges, cells of the innate system become epigenetically reprogrammed and establish immune memory. Read more

Supervisors: Dr F Errington-Mais, Dr P Laslo

Open Day(s) Year round applications PhD Research Project Self-Funded PhD Students Only

More Details

We have 128 Biological Sciences PhD Research Projects PhD Projects, Programmes & Scholarships in Bradford

Biological Sciences PhD Research Projects PhD Projects, Programmes & Scholarships in Bradford

We have 128 Biological Sciences PhD Research Projects PhD Projects, Programmes & Scholarships in Bradford

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