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We have 19 Biological Sciences (adhesion) PhD Projects, Programmes & Scholarships

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Biological Sciences (adhesion) PhD Projects, Programmes & Scholarships

We have 19 Biological Sciences (adhesion) PhD Projects, Programmes & Scholarships

Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

  Research Group: Institute of Cancer Therapeutics
Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Polysialyltransferases as a target in metastatic cancer

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more

Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more

Investigating molecular drivers of cell invasion

The Wells laboratory focusses on exploring the molecular mechanisms that underlie cell invasion. We have interests in cancer cell invasion and hemopoietic cell invasion. Read more

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