Biological Sciences (bone) PhD Projects, Programmes & Scholarships

We have 37 Biological Sciences (bone) PhD Projects, Programmes & Scholarships

Investigating the links between β-amyloid, osteoporosis and frailty in Alzheimer’s disease

Queen Mary University of London Institute of Dentistry

Background. Individuals with Alzheimer’s disease are more likely to suffer from osteoporosis (the loss of bone mass and strength) than age-matched individuals1, significantly contributing to the frailty associated with dementia. Read more

Supervisors: Dr S McArthur, Dr SCF Rawlinson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Control of bone shape and function by the extracellular matrix Fibrillin-1

University of Liverpool Institute of Life Course and Medical Sciences

Bones are tightly regulated structures that remodel their structure to adapt to changes in their mechanical environment. With ageing, this mechanical response is often dampened, leading to bone loss and weakness. Read more

Supervisor: Dr B Poulet

Year round applications PhD Research Project Self-Funded PhD Students Only

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Elucidation of a new pathological mechanism for brittle bone disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

The incidence of the brittle bone disease osteogenesis imperfecta (OI) is estimated to be around 1 in 10,000 individuals. The phenotypic spectrum of OI ranges from mild to perinatal lethal and includes extra-skeletal connective tissue manifestations. Read more

Supervisor: Dr EG Laird

Year round applications PhD Research Project Self-Funded PhD Students Only

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Unravelling the role of P4HB in skeletal development: towards treatment of heritable bone fragility

University of Sheffield School of Medicine and Population Health

Osteogenesis Imperfecta (OI) affects 1 in 15-20,000 live births and results in a childhood with frequent fractures, reduced mobility and joint problems. Read more

Supervisor: Dr M Balasubramanian

Year round applications PhD Research Project Self-Funded PhD Students Only

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Precision Therapy for NBAS-related disorder

University of Sheffield School of Medicine and Population Health

It is very well recognised that rare diseases offer the potential to uncover new information about mechanisms underlying a range of phenotypes. Read more

Supervisor: Dr M Balasubramanian

Year round applications PhD Research Project Self-Funded PhD Students Only

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Importance of RARγ for malignant potential of AML blasts

Medical University of Vienna Institute for Pathophysiologie and Allergy

The Doctoral Candidate (DC) will determine the roles of retinoic acid receptors (RAR) α and γ in the development of acute myeloid leukaemia (AML). Read more

Supervisor: Prof E Marcinkowska

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Cell-matrix interface engineering for regenerative medicine applications and disease modelling

The University of Manchester Faculty of Biology, Medicine and Health

Dr. Mahetab Amer is seeking motivated students with backgrounds in tissue engineering, cell biology, materials science, or related fields to join her dynamic, multidisciplinary research group at the Division of Cell Matrix Biology and Regenerative Medicine, University of Manchester. Read more

Supervisor: Dr M.A Amer

Year round applications PhD Research Project Self-Funded PhD Students Only

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Targeting dormant cancer cells in myeloma

University of Sheffield School of Medicine and Population Health

Multiple myeloma is the second most common blood cancer and remains essentially incurable. Chemotherapy is effective at reducing tumour and extends survival, but it never fully eradicates disease, so patients face inevitable relapse. Read more

Supervisors: Dr A Green, Prof S El-Khamisy

31 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Using pre-clinical models of disease to define new targets to slow joint degeneration in osteoarthritis

University of Liverpool Institute of Life Course and Medical Sciences

The main overall aim of this project is to understand mechanisms of joint degeneration during osteoarthritis progression in order to define new targets for therapy. Read more

Supervisor: Dr B Poulet

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the neuro-stromal-immune interactions in inflammageing and osteoarthritis.

University of Greenwich School of Pharmacy (Medway Campus)

Ageing is associated with a higher risk of developing multiple chronic conditions (multimorbidity) including osteoarthritis. Age-associated chronic low-grade inflammation (inflammageing) is a hallmark of osteoarthritis. Read more

Supervisor: Dr S Ashraf

Year round applications PhD Research Project Self-Funded PhD Students Only

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Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

University College London UCL Cancer Institute

Cancer is the leading cause of death in children and the second in young adults in England and Wales. Sarcomas, tumours that originate from connective tissues (bone, muscle, fat), account for around 15% of childhood cancers. Read more

Supervisors: Dr M Secrier, Dr L Cottone

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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NIHR Leeds BRC: Pre-clinical evaluation of novel regenerative medicine strategies for knee osteoarthritis

University of Leeds Faculty of Medicine and Health

Historically, articular cartilage was considered incapable of spontaneous repair. However, biomechanical correction in osteoarthritis (OA) using high tibial osteotomy or joint distraction demonstrated the remarkable joint to regeneration by “merely” correcting joint alignment. Read more

Supervisors: Prof H Pandit, Prof D McGonagle

26 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Revealing the correlation between physiology and physical chemistry of microcalcification in connective tissue using AI supported tissue characterization.

University of York School of Physics, Engineering and Technology

A fundamental component of human body is connective tissue which serves various structural and supportive functions including skin integrity, abdominal wall enforcement and bone formation. Read more

Supervisors: Dr M Chauhan, Dr R Kroger

Year round applications PhD Research Project Self-Funded PhD Students Only

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Improving patient outcomes following mandibular reconstruction after oral cancer: novel finite element methods for better surgical design

University of Liverpool Institute of Life Course and Medical Sciences

Within Cheshire & Merseyside over 1,000 individuals a year are diagnosed with head and neck cancer, with some central city wards having 4 times the UK average. Read more

Supervisors: Dr A Sharp, Prof AS Schache

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

University of Nottingham School of Pharmacy

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 37 Biological Sciences (bone) PhD Projects, Programmes & Scholarships

Biological Sciences (bone) PhD Projects, Programmes & Scholarships

We have 37 Biological Sciences (bone) PhD Projects, Programmes & Scholarships

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