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We have 11 Biological Sciences (rheumatoid) PhD Projects, Programmes & Scholarships

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Biological Sciences (rheumatoid) PhD Projects, Programmes & Scholarships

We have 11 Biological Sciences (rheumatoid) PhD Projects, Programmes & Scholarships

(MRC DTP CASE) Investigating the mechanisms contributing to impaired regulatory function of B cells in autoimmunity

The implementation of biological therapies has significantly advanced the management of autoimmune diseases (AIDs). However, the failure to achieve clinical remission in ‘non-responders’ remains a significant and unmet challenge. Read more

Interdisciplinary investigation of a large effect of sulfasalazine on HbA1c

The anti-inflammatory drug sulfasalazine, which is used in rheumatoid arthritis and inflammatory bowel disease, was reported earlier to suppress HbA1c in a small cohort of patients [1]. Read more

Helminth products as macrophage “trainers”: a novel tool to induce anti-inflammatory trained immunity

The innate immune system can display characteristics of immunological memory. This phenomenon, termed “trained immunity”, refers to the long-term functional reprogramming of innate immune cells after the encounter with infectious or non-infectious agents that influences their capacity to respond to a secondary stimulus. Read more

Molecular Mechanisms of Resolution of Inflammation

We are seeking talented, motivated students to join the research group led by Professor Andy Clark (https://www.birmingham.ac.uk/staff/profiles/inflammation-ageing/clark-andy.aspx), a member of the University of Birmingham’s Rheumatology Research Group (https://www.birmingham.ac.uk/research/inflammation-ageing/research/rheumatology-research-group/index.aspx). Read more

Investigating the genetic basis of immunological overlap between inflammatory diseases

Genetic studies have identified numerous variants within the human genome associated with susceptibility to common complex inflammatory diseases, such as rheumatoid arthritis (RA) and ulcerative colitis (UC). Read more

The Survivin Interactome in Health and Disease

Survivin is a small protein that is essential for life but that also contributes to disease, most notably cancer, in which its abnormal overexpression is linked to therapeutic resistance and metastasis. Read more
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