Biological Sciences (synthetic chemistry) PhD Projects, Programmes & Scholarships

We have 43 Biological Sciences (synthetic chemistry) PhD Projects, Programmes & Scholarships

Tailoring Unspecific Peroxygenases (UPOs) for Applications in Synthetic Organic Chemistry

University of York Department of Chemistry

Background. The oxygenation of organic compounds presents an ongoing challenge to synthetic chemistry as conventional reagents present difficulties with toxicity, harsh conditions and poor selectivity. Read more

Supervisors: Prof G J Grogan, Dr W Unsworth, Dr J Cartwright

20 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Phosphine Oxides as Rising Stars in Drug Discovery

Imperial College London Institute of Chemical Biology

Phosphine oxides represent a noticeably underrepresented chemotype in drug discovery. Read more

Supervisor: Dr J Bull

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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New tools for old foes: developing a new class of antimicrobial metallodrugs (LORD_U24DTP)

University of East Anglia School of Chemistry

Primary Supervisor: Dr Rianne Lord . Secondary Supervisor: Professor Mark Webber (QIB) . Read more

Supervisor: Dr R Lord

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Investigation of the critical roles of platelets at the interface between thrombosis and inflammation in order to develop improved therapeutic strategies for the treatment and/or prevention of cardiovascular/inflammatory diseases

University of Reading School of Pharmacy

Platelets (small circulating blood cells) are involved in blood clotting to prevent excessive bleeding, however, their inappropriate activation under pathological conditions leads to thrombosis resulting in major cardiovascular diseases such as heart attack and stroke. Read more

Supervisor: Prof SV Vaiyapuri

Year round applications PhD Research Project Self-Funded PhD Students Only

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How do RNA-binding proteins control splice site selection? A multi-disciplinary approach

University of Leicester Molecular and Cell Biology

Almost every protein-coding gene in vertebrates can and does express multiple proteins. This is achieved primarily by RNA splicing, which is an essential step in gene expression in mammals and generates incredible diversity. Read more

Supervisors: Prof I Eperon, Prof A Hudson, Dr C Dominguez

Year round applications PhD Research Project Self-Funded PhD Students Only

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Novel strategies for the diagnosis and treatment of snakebites

University of Reading School of Pharmacy

Snakebite envenomation (SBE), a high priority neglected tropical disease affects several million people worldwide resulting in as many as 150,000 deaths and around 500,000 permanent disabilities every year. Read more

Supervisor: Prof SV Vaiyapuri

Year round applications PhD Research Project Self-Funded PhD Students Only

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Targeting glycans on the outside of cells, as new therapeutics

The University of Manchester Department of Chemistry

Most drugs have intracellular targets (proteins etc). This creates a barrier to how to target a cell, and then get the drug inside the cell. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Building new nano-biosensors for healthcare: Linking biology to the world of carbon nanotechnology through synthetic biology

Cardiff University Cardiff School of Biosciences

Project Descriptions. Proteins are nature’s very own molecular machines carrying out functions ranging from catalysis to molecular recognition to energy conversion. Read more

Supervisors: Prof D Jones, Dr M Palma, Dr WK Kelton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Developing novel targeted therapeutic approaches through induced-proximity of proteins

University of Dundee School of Life Sciences

Protein post-translational code is at the heart of protein function and signal transduction in cells. Enzymes catalyse the addition or removal of post-translational modifications (PTM), such as phosphorylation, methylation, acetylation, and ubiquitylation, on proteins. Read more

Supervisors: Prof G Sapkota, Prof A Ciulli

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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High-throughput biomaterials discovery

The University of Manchester Department of Chemistry

Polymer biomaterials have revolutionised a range of areas from drug delivery, to antimicrobials, to cellular cryopreservation. There are 1000’s of possible monomer combinations, molecular weights and architectures to be explored, and even small differences can dramatically change their properties. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Synthetic Protein-Transporters for Enhanced Transduction Activity

Queen’s University Belfast School of Pharmacy

Intracellular protein delivery is key to probing important cellular processes and developing advanced biotherapeutics. However, protein trafficking into the cell, and more specifically to the cytosol remains a significant challenge. Read more

Supervisor: Dr S Carmali

Year round applications PhD Research Project Self-Funded PhD Students Only

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An Interdisciplinary Approach to Developing of Macrocyclic Inhibitors of the MAPK Pathway

University of Southampton Faculty of Engineering and Physical Sciences

Supervisory Team: Prof Ali Tavassoli . Project Description. We are seekign an outstanding chemistry student with an interest in chemical biology to work on a project to develop cyclic peptide inhibitors of a protein-protein interaction that is heavily implicated in the development and growth of tumours. . Read more

Supervisor: Prof A Tavassoli

31 August 2024 PhD Research Project Competition Funded PhD Project (European/UK Students Only)

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Enantioselective Fluorinations with the Hypervalent Fluoroiodane Reagent

University of Leicester Department of Chemistry

Graduate Teaching Assistantship. This is a Graduate Training Assistantship (GTA), which means that you will be required to do some teaching, particularly lab demonstrating, as part of your training. Read more

Supervisors: Dr A Stuart, Dr A Pulis

22 April 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

The University of Manchester Department of Chemistry

Ecteinascidin 743 (ET-743, Trabectedin) is a marine-derived natural organic compound approved for the treatment of soft tissue sarcomas. Read more

Supervisors: Prof E Takano, Prof H Oguri

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Bio self-assembled molecular wires

University of Birmingham School of Chemistry

Biology has evolved sophisticated ligands for metal ion coordination in the form of proteins. Read more

Supervisor: Dr A Peacock

1 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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We have 43 Biological Sciences (synthetic chemistry) PhD Projects, Programmes & Scholarships

Biological Sciences (synthetic chemistry) PhD Projects, Programmes & Scholarships

We have 43 Biological Sciences (synthetic chemistry) PhD Projects, Programmes & Scholarships

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