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We have 58 Agricultural Sciences PhD Projects, Programmes & Scholarships in Loughborough

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Agricultural Sciences PhD Projects, Programmes & Scholarships in Loughborough

We have 58 Agricultural Sciences PhD Projects, Programmes & Scholarships in Loughborough

Loughborough University

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Understanding control of genome folding by cohesin

University of Leicester Molecular and Cell Biology
Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more
 Supervisors: Prof D Panne, Dr T Schalch
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Revealing Reactivity in Cancer-Associated Heme Proteins: Novel Time-Resolved Structural Approaches

University of Leicester Molecular and Cell Biology
Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme-containing enzyme involved in the degradation of tryptophan to kynurenine. Cancer cells upregulate IDO1 to escape normal immune responses and, in many cases, a high expression of IDO1 is connected to poor prognosis. Read more
 Supervisors: Dr HK Kwon, Dr P A Ash
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Evaluating the impact of genotoxic aldehyde stress in premature ageing

University of Leicester Department of Chemistry
Aldehydes are highly reactive chemicals that are common pollutants and human metabolites. However, the vast majority of aldehydes’ biological functions are unknown. Read more
 Supervisors: Dr R Hopkinson, Dr K Tanaka
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Chemical energy conversion in biology studied using advanced spectroscopic and structural tools

University of Leicester Department of Chemistry
Redox properties of metal-containing active sites are critically important to many biocatalytic processes. one third of all proteins contain a redox-active metal, and ca 22% of submissions to the Protein Data Bank contain a transition metal. Read more
 Supervisors: Dr PA Ash, Dr H Kwon
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Natural products in bacterial physiology and chemical interaction

University of Leicester Department of Genetics and Genome Biology
Microbial natural products have diverse chemical structures and bioactivities, which range from cell-cell signalling, nutrient acquisition, antifungal and antibacterial activity to stress resistance (1). Read more
 Supervisors: Dr C Jenul, Prof D Jones
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Visual and oculomotor limitations on time pressured text comprehension: Implications for decision-making

University of Leicester School of Psychology and Vision Sciences
Background: . The proposed project brings together two very different areas of research. First, the visual and oculomotor (eye movement control) mechanisms involved in reading. Read more
 Supervisors: Dr SW White, Dr E Krockow
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Short and long-term genetic and behavioural consequences of traumatic brain injury in fruit flies

University of Leicester Department of Genetics and Genome Biology
General background . How many fingers am I holding up? What day of the week is it? Follow my finger? These three questions are designed to test your sensory, memory and motor neural abilities following an accident; all three systems are affected by a severe deceleration of your brain. Read more
 Supervisors: Dr B Warren, Dr E Rosato, Dr R Feuda
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Understanding the role of pigmentation in retinal and vision development

University of Leicester School of Psychology and Vision Sciences
Establishing structure-function correlations in vision development  . The aim of this project is to develop methods to study the relationship between pigmentation and vision development in humans and zebrafish.  . Read more
 Supervisors: Dr M Thomas, Dr W Norton, Dr J McDearmid
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Nuclear and transcriptional dysregulations during cellular senescence

University of Leicester Molecular and Cell Biology
Cellular senescence, which is characterised by a proliferation arrest, is a driver of ageing (1). Several stresses can induce cellular senescence, including persistent DNA damage, telomere dysfunction, and oncogene activation. Read more
 Supervisors: Dr MT Tellier, Dr Y Markaki
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Obtaining insights into how a signalling hub protein Ras activates multiple effectors

University of Leicester Molecular and Cell Biology
The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more
 Supervisors: Dr K Tanaka , Dr R Mahen
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Unlocking the Secrets of Genome Regulation through cryo-EM

University of Leicester Molecular and Cell Biology
Are you an ambitious spirit, ready to make breakthrough discoveries at the frontier of epigenetics? Dive deep into the fascinating world of eukaryotic genomes with us! . Read more
 Supervisors: Dr T Schalch, Dr AC Chaplin
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Using measures of eye movements and EEG to understand effects of cognitive ageing on reading

University of Leicester School of Psychology and Vision Sciences
Healthy ageing is associated with reductions in visual and cognitive abilities that are required for many activities of daily life (e.g., reading, navigation, object-finding). Read more
 Supervisors: Prof K Paterson, Dr A Pagán
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Molecular level understanding of Mycobacterium tuberculosis

University of Leicester Department of Respiratory Sciences
Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more
 Supervisors: Dr H O'Hare, Dr N Garton
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Failures to detect language errors during older age: Evidence of cognitive decline?

University of Leicester School of Psychology and Vision Sciences
Healthy ageing is associated with well-recognised cognitive decline across multiple domains from age 50 onwards (e.g., working memory, processing speed). Read more
 Supervisors: Dr V McGowan, Dr S Gunn
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Epigenetics of early human development: From molecular mechanisms to regenerative medicine

University of Leicester Molecular and Cell Biology
Ever wondered how nature maintains balance of gene expression between sex chromosomes? Well, the 46th chromosome of XX females, the second X, has to be switched off. Read more
 Supervisors: Dr Y Markaki, Dr T Schalch
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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