University of Dundee Agricultural Sciences PhD Projects, Programmes & Scholarships

We have 87 University of Dundee Agricultural Sciences PhD Projects, Programmes & Scholarships

Investigating mechanisms of extra-cellular matrix remodelling and fibrosis in the gastrointestinal tract

Inflammatory bowel diseases, such as Crohn's disease, are increasing in prevalence globally. These are caused by chronic inflammation in the gut, there is no cure and medications are not effective for all. Read more

Supervisor: Dr M Mclean

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Regulation of protein palmitoylation in the heart by persulphidation

University of Dundee School of Medicine

Hydrogen sulphide (H2S) is known to have cardioprotective qualities. Persulphidation is a reversible post-translational modification (PTM) in which a persulphide group is formed by the reaction of H2S with the thiol groups of cysteine residues in proteins. Read more

Supervisors: Dr N Fraser, Dr C Murdoch

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Mechanism, cellular consequences and pharmacological manipulation of Ras palmitoylation for the treatment of cancer

University of Dundee School of Medicine

In humans, the genes HRAS, NRAS and KRAS encode three closely related proteins frequently mutated in cancer promoting unregulated cell growth. Read more

Supervisors: Dr N Fraser, Dr G Masson

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Leveraging novel automated diagnostic pathways with augmented precision medicine approaches for the early detection and risk stratification of liver disease

University of Dundee School of Medicine

Liver disease represents one of the fastest-growing causes of morbidity and mortality in the world. The principle aetiological variants are contained within the new nomenclature of steatotic liver disease (SLD). Read more

Supervisors: Dr P Brennan, Prof J F Dillon, Dr M Al-Khairalla

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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The effect of early-life stress on cardiac function in later life

University of Dundee School of Medicine

Stressful experiences in early childhood can increase the risk of cardiovascular disease (CVD) in later life. How early-life stress (ELS) influences susceptibility to CVD onset remains largely unknown. Read more

Supervisors: Dr N Fraser, Dr C Murdoch, Prof T Hales

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Vascularisation of tumour organoids for mechanistic and drug development

University of Dundee School of Medicine

Gliomas such as are the most common form of brain tumour, a subset Glioblastoma (GBM) are devastating adult brain cancer with high rates of recurrence and treatment resistance. Read more

Supervisors: Dr C Murdoch, Dr S Banerjee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Identifying secreted biomarkers in brain cancer

University of Dundee School of Medicine

Stage IV brain cancer or glioblastoma (GBM) poses a major challenge with only 5 FDA approved chemotherapeutic drugs available for treatment. Read more

Supervisor: Dr S Banerjee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Utility of in silico prediction tools to aid variant interpretation

University of Dundee School of Medicine

Accurate variant interpretation represents is essential for the successful implementation of genetic testing in the clinical setting. Read more

Supervisor: Dr P Newey

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigating how dormant senescent cells can drive drug-resistance following chemotherapy

University of Dundee School of Medicine

Most anti-cancer chemotherapeutics work by inducing DNA damage and arresting the cell cycle in either G1 or G2 phase. A frequent outcome of this arrest is that cells exit the cell cycle into a state known as senescence. Read more

Supervisors: Dr A Saurin, Dr T Ly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Using chemical-genetics to inhibit and characterise “undruggable” enzymes

University of Dundee School of Medicine

The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more

Supervisors: Dr A Saurin, Dr T Ly

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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The Holistic Microbiome in Health and Disease: Linking the Oral, Gut and Respiratory Microbiomes

University of Dundee School of Medicine

The human gut microbiome is recognised as a major determinant of health and disease. Studies to date, including those of the international Human Microbiome Project, have largely focused on individual body sites such as nose or mouth or faeces. Read more

Supervisors: Dr R Hansen, Dr A Dicker, Dr C Mowat

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigating Nutrient-Dependent Regulation of Microglia Function and Immune Responses

University of Dundee School of Life Sciences

Funding – Tenovus Scotland funded 4-year studentship, providing tuition fees, training/research costs and an annual tax free stipend of £19,237, increasing annually according to the UKRI rate. Read more

Supervisors: Dr A Lloyd, Prof D Cantrell

7 June 2024 PhD Research Project Competition Funded PhD Project (European/UK Students Only)

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Fertility preservation of male childhood cancer patients

University of Dundee School of Medicine

Every day, around five children receive a diagnosis of cancer in the United Kingdom, with boys slightly more frequently than girls. Read more

Supervisors: Dr F Lopes, Prof R Mitchell

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Examining the dysfunction of DNA damage repair in synucleinopathies

University of Dundee School of Medicine

DNA damage is an emerging stressor implicated in the pathogenesis of neurodegenerative diseases. Our recent research within post-mortem dementia with Lewy body brain tissue has highlighted the dysregulation of several DNA damage repair pathways, alongside the occurrence of a novel nuclear alpha-synuclein pathology. Read more

Supervisor: Dr D Koss

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigating Lysosomal Dysfunction in Ageing and Neurodegeneration

University of Dundee School of Medicine

Lysosomes are key cellular organelles that degrade and recycle macromolecules, act as signalling hubs and are implicated in many diseases including Parkinson’s disease (PD) and Alzheimer’s dementia (AD) where old age is a major risk factor. Read more

Supervisor: Dr E Sammler

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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We have 87 University of Dundee Agricultural Sciences PhD Projects, Programmes & Scholarships

University of Dundee Agricultural Sciences PhD Projects, Programmes & Scholarships

We have 87 University of Dundee Agricultural Sciences PhD Projects, Programmes & Scholarships

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