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We have 46 Chemistry (drug discovery) PhD Projects, Programmes & Scholarships

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Chemistry (drug discovery) PhD Projects, Programmes & Scholarships

We have 46 Chemistry (drug discovery) PhD Projects, Programmes & Scholarships

Small molecule cancer drug discovery targeting resistant disease.

Despite continuous advances in targeted cancer therapy in recent years, there remains a major challenge to combat drug resistance and poor levels of efficacy in areas of unmet medical need, such as advanced colorectal and breast cancer. Read more

Pharmacokinetics Guided Natural Products Exploration for Drug Discovery, Development, Delivery and Therapy

  Research Group: Institute of Cancer Therapeutics
Natural products have emerged as a key standard in novel and safe delivery of anticancer bioactive compounds. Apart from their ease of administration and delivery, natural/phytochemicals still face several hurdles, due to their physiochemical and pharmacokinetic properties. Read more

Photoredox molecular editing for enhanced drug discovery

Molecular editing platforms, the process by which single atoms can be inserted or deleted selectively in or around a molecule’s skeleton, are transformative to synthetic chemists across industry and academia for the streamlined development of new drugs. Read more

Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

  Research Group: Astbury Centre for Structural Molecular Biology
Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more

Towards the development of a novel class of broad-spectrum anti-infective drugs

Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more

Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more

Predicting drug solubility in different solvents using molecular simulation and machine learning

Predicting the solubility of complex drug-like molecules is crucial at several stages of the drug discovery and manufacture. In particular, solvent selection has been highlighted as a crucial step in process design and optimisation [1]. Read more

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