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Computer Science (genetic) PhD Projects, Programmes & Scholarships

We have 44 Computer Science (genetic) PhD Projects, Programmes & Scholarships

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AI-Driven Discovery of Genetic Markers in Developmental Disorders

Edinburgh Napier University School of Computing, Engineering & the Built Environment
Developmental disorders (DDs) are defined as a group of conditions manifesting as cognitive, social, and motor dysfunctions The existing literature showcases the potential of Artificial Intelligence (AI) and genomics in advancing our understanding and diagnosis of DDs. Read more
 Supervisor: Dr LL La Spada
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The genetic map of human molecular phenotypes

University of Bristol Bristol Medical School
Rationale. Genome wide associations studies (GWASs) have discovered many genetic associations with a large range of human traits, but the functional consequences of GWAS signals often remain elusive, as most GWAS signals reside in non-coding genomic regions. Read more
 Supervisors: Dr J Min, Dr G Hemani, Dr JH Hawe
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Functional Mechanisms of Genetic Risk Factors for Immune-Related Disease

King’s College London School of Medicine
Who are we?. Read more
 Supervisor: Prof T Vyse
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Precision Diagnosis for Congenital Anomalies – using AI & leveraging multimodality data to help counsel parents appropriately in rare diseases.

Great Ormond Street Hospital for Children NHS Trust GOSH BRC Applied Child Health Informatics Theme (Non-Clinical) PhD Studentships
Skeletal dysplasias are a heterogenous group of congenital bone and cartilage disorders with genetic etiology. There are currently 461 recognised diseases that fall into this category. Read more
 Supervisors: Dr S Shelmerdine, Prof I Drobnjak, Prof O Arthurs
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Using nutrigenetic, nutrigenomic and machine learning approaches to investigate the risk of cardiometabolic disease-related traits in ethnically diverse populations.

University of Reading Department of Food and Nutritional Sciences
This PhD project represents an exciting opportunity to develop and conduct research at the forefront of nutritional and genetic epidemiology, contributing to the prediction, prevention, and better understanding of the development of non-communicable diseases such as obesity and diabetes, using datasets from multiple ethnic groups. Read more
 Supervisor: Dr V Karani
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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VariantVisualiser: Ensuring precise diagnoses of genetic disorders through the development of intuitive software that facilitates the integration and visualisation of complex informatics with biological and clinical data.

The University of Manchester Department of Computer Science
Rare diseases affect <1-in-2,000 people, but ~8,000 rare genetic diseases impact ~10% of births globally. These arise from variations in patients’ DNA sequences. Read more
 Supervisors: Dr S Pettifer, Dr PF Freeman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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VariantVisualiser: Ensuring precise diagnoses of genetic disorders through the development of intuitive software that facilitates the integration and visualisation of complex informatics with biological and clinical data

The University of Manchester Faculty of Biology, Medicine and Health
Rare diseases affect. This proposal builds on substantial efforts of a Human Genome Organization committee which has proposed a unified professional-standard for representing genomic data which, when finalised, will be adopted world-wide. Read more
 Supervisors: Dr S Pettifer, Dr PF Freeman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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NIHR Leeds BRC: Utilising genetic and genomic predictors of vasculitis and disease/treatment complications for application in routine clinical practice

University of Leeds Faculty of Medicine and Health
There is substantial interest in using genetic biomarkers to predict those most at risk of disease and treatment complications; this is one of the focuses of Our Future Health, a national study aiming to recruit 5M participants ( https://ourfuturehealth.org.uk/ ). Read more
 Supervisors: Prof A Morgan, Dr MM Iles, Dr R Mujica-Mota
 26 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Early life factors in the development of Juvenile idiopathic arthritis

The University of Manchester Faculty of Biology, Medicine and Health
Juvenile idiopathic arthritis (JIA) is an autoimmune inflammatory arthritis with disease onset before the age of 16. Children and young people with this condition develop painful swollen joints and untreated it can lead to long term disability. It may also be associated with comorbid conditions such as uveitis. Read more
 Supervisors: Dr J Humphreys, Dr J Bowes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Using Generative AI to Draw Diagrams

Edinburgh Napier University School of Computing, Engineering & the Built Environment
Designing algorithms for human-readable, effective diagrams is difficult. The algorithm must be able to handle a broad range of datasets, some of which will not readily lend themselves to visualisation. Read more
 Supervisors: Dr P Chapman, Dr K Sim
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Experimental and computational Cancer PhD: Overcoming osteosarcoma chemoresistance by characterizing and targeting cellular quiescence

University College London UCL Cancer Institute
Cancer is the leading cause of death in children and the second in young adults in England and Wales. Sarcomas, tumours that originate from connective tissues (bone, muscle, fat), account for around 15% of childhood cancers. Read more
 Supervisors: Dr M Secrier, Dr L Cottone
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Identifying variants impacting splicing of 5’ and 3’ UTRs and underpinning inherited retinal disease

The University of Manchester Faculty of Biology, Medicine and Health
Genomic variation that impacts splicing is well established as a cause of genomic disorders, but is almost exclusively limited to protein-coding exons and introns intersecting protein-coding exons. Read more
 Supervisors: Dr J Ellingford, Prof R O'Keefe
 15 June 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Understanding the ecological and evolutionary effects of heatwaves in tropical species and ecological communities

James Cook University College of Science and Engineering
Heatwaves are considered one of the most threatening processes for our plants and animal species as the Earth’s climate warms. There is much to understand about how our species and the ecological communities they form will change and adapt through heatwaves. Read more
 Supervisor: Dr MH Higgie
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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A deep-learning approach to genomic regulation of tissue-specific alternative splicing

The University of Manchester Faculty of Biology, Medicine and Health
Each human gene is a blueprint for multiple distinct RNA transcripts that can be produced in differing quantities based on the localisation of the transcribing… Read more
 Supervisors: Dr JE Eales, Prof T Papamarkou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

University of Bristol Bristol Medical School
The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more
 Supervisor: Prof T Gaunt
 20 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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