We have 49 University of Dundee, School of Life Sciences PhD Projects, Programmes & Scholarships

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University of Dundee, School of Life Sciences PhD Projects, Programmes & Scholarships

We have 49 University of Dundee, School of Life Sciences PhD Projects, Programmes & Scholarships

Investigating Nutrient-Dependent Regulation of Microglia Function and Immune Responses

University of Dundee School of Life Sciences

Funding – Tenovus Scotland funded 4-year studentship, providing tuition fees, training/research costs and an annual tax free stipend of £19,237, increasing annually according to the UKRI rate. Read more

Supervisors: Dr A Lloyd, Prof D Cantrell

7 June 2024 PhD Research Project Competition Funded PhD Project (European/UK Students Only)

MSc by Research: Speeding up the plant microbiota: investigating the impact of speed breeding on host-microbe interactions in the barley rhizosphere

University of Dundee School of Life Sciences

Feeding a growing world population amid climatic modifications and international conflicts represents an unprecedent challenge for crop production. Read more

Supervisors: Dr D Bulgarelli, Dr C Campoli

Year round applications PhD Research Project Self-Funded PhD Students Only

BARIToNE: Improving barley climate resilience using a candidate gene approach (Project code 24H)

University of Dundee School of Life Sciences

Supervisors. Lead supervisor - Dr Martin Balcerowicz, University of Dundee. Second supervisor - Dr Craig Simpson, James Hutton Institute. Read more

Supervisors: Dr M Balcerowicz, Dr C Simpson, Ms G MacDonald

31 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

BARIToNE: Deep Seeded: Improving barley for deeper sowing (Project code 24I)

University of Dundee School of Life Sciences

Supervisors. Lead supervisor - Dr Sarah McKim, University of Dundee. Second supervisor - Dr Chiara Campoli, James Hutton Institute. Read more

Supervisors: Dr S McKim, Dr C Campoli, Dr L Ramsay, Dr D Sparkes

31 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

BARIToNE: Barley productivity and nitrogen losses under climate change in Scotland (Project code 24F)

University of Dundee School of Life Sciences

Supervisors. Lead supervisor - Dr Mike Rivington, James Hutton Institute. Second supervisor - Prof John Rowan, University of Dundee. Read more

Supervisors: Dr M Rivington, Prof J Rowan, Dr D Sparkes

31 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

University of Dundee School of Life Sciences

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Supervisors: Prof G Sapkota, Dr S Virdee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

Regulation and mechanics in polarity

University of Dundee School of Life Sciences

Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. Read more

Supervisor: Dr D H Murray

30 June 2024 PhD Research Project Self-Funded PhD Students Only

MSc by Research: Signaling pathways controlling epidermal development in cereals

University of Dundee School of Life Sciences

Plants living on land face brutal threats from pests, dehydration and temperature. To survive and thrive, land plants evolved a waxy ‘cuticle’ and distinctive epidermal cells such as gas pores and defensive barbs. Read more

Supervisor: Dr S McKim

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Jasmonate control of barley development

University of Dundee School of Life Sciences

From the earliest farmers to modern plant breeders, humans have continually modified the body plan of cereals, sometimes drastically, to generate higher grain yields. Read more

Supervisor: Dr S McKim

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: The Generation Gap – understanding tissue communication during grain development

University of Dundee School of Life Sciences

Cereal grain provides more calories than any other source to our diet, making grain production vital to food security. We study grain development in barley, a globally important cereal, and a powerful genetic model system. Read more

Supervisor: Dr S McKim

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Regulation of Architecture in Barley

University of Dundee School of Life Sciences

Plant architecture, or body plan, plays a key role in determining grain yield of crop plants. However, we have little understanding of the molecular genetic basis of architecture in the temperate cereals such as barley (Hordeum vulgare L.), especially in comparison to the warm weather crops such as rice (Oryza sativa). Read more

Supervisor: Dr S McKim

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Bacillus subtilis biofilm formation and environmental stress

University of Dundee School of Life Sciences

Bacillus subtilis is a Gram-positive, spore-forming bacterium that is widely used as a model organism to increase our understanding of biofilm formation. Read more

Supervisors: Prof N Stanley-Wall, Dr S Coulthurst

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Bacillus subtilis intraspecies interactions

University of Dundee School of Life Sciences

Bacillus subtilis is a Gram-positive, spore-forming bacterium that resides in intestinal tracts, soil, and on plant surfaces. B. subtilis, alongside other Bacillus species, presents a promising plant growth–promoting rhizobacteria. Read more

Supervisors: Prof N Stanley-Wall, Dr S Coulthurst

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Investigation of the interplay between the cell cycle and Notch intracellular domain levels in presomitic mesoderm cells in somitogenesis

University of Dundee School of Life Sciences

One of the key processes in embryo development is somitogenesis. This is the formation of segments, known as somites, that go on to develop into bone and skeletal muscle. Read more

Supervisor: Prof J K Dale

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Function of presomitic mesoderm specific phosphorylation of the Notch intracellular domain in somitogenesis

University of Dundee School of Life Sciences

The Notch signalling pathway is one of the key pathways required for the developing embryo. It is especially important for the process of somitogenesis, the formation of body segments that develop into e.g. Read more

Supervisor: Prof J K Dale

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: m6A modification of segmentation clock mRNAs and its role in somitogenesis

University of Dundee School of Life Sciences

During early embryogenesis, segments (somites) are formed during a process called somitogenesis. These somites will go on to form the bones and muscles of the skeleton. Read more

Supervisors: Prof J K Dale, Dr P Murray

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Degrade or die: Understanding proteasome regulation upon stress

University of Dundee School of Life Sciences

The Rousseau lab is interested in decoding how protein degradation by the proteasome is regulated in cells so that accumulation of unfolded, misfolded, or damaged proteins can be cleared before they become deleterious. Read more

Supervisor: Dr A Rousseau

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Nutrient-dependent regulation of microglia function and immune responses

University of Dundee School of Life Sciences

Microglia are constantly sensing the brain environment for metabolic changes, damage and pathogenic invasion. Microglia are highly metabolically active, with activation in response to inflammatory stimulation increasing glycolytic demand. Read more

Supervisors: Dr A Lloyd, Dr L Sinclair

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Resolving immune cell proteomes to subcellular resolution

University of Dundee School of Life Sciences

Immune activation triggers dramatic proteome remodelling. Using high sensitivity mass spectrometry we have mapped immune cell proteomes, providing novel insights into immune cell phenotypes and revealing the metabolic and protein synthesis machinery and environmental sensors that shape cell fate. Read more

Supervisor: Dr A Howden

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Molecular Analysis of Nuclear Bodies and RNP Trafficking Pathways in the Cell Nucleus

University of Dundee School of Life Sciences

Many important processes within mammalian cells are compartmentalised within specific subcellular structures. In the cell nucleus, Nuclear Bodies (NBs), such as nucleoli, provide specialised compartments that are not surrounded by membranes, but still concentrate specific proteins and RNAs. Read more

Supervisor: Prof A I Lamond

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Regulation of Kinetochore function by PLK1

University of Dundee School of Life Sciences

Accurate partition of the duplicated genome during cell division is crucial for cellular viability and organismal development. Chromosome mis-segregation is a major source of aneuploidy and it is a hallmark of cancer, while in oocytes represents the major source of miscarriages and genetic disease. Read more

Supervisor: Dr F G Pelisch

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Deciphering the role(s) of Cdk1 during oocyte meiosis

University of Dundee School of Life Sciences

Meiosis is a specialised type of cell division that produces haploid daughter cells known as gametes that are important for sexual reproduction. Read more

Supervisor: Dr F G Pelisch

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Investigation of coordination of cell divisions during early embryonic development

University of Dundee School of Life Sciences

Gastrulation is an essential process in early development, during which the forming ectoderm, mesoderm and endoderm take up their correct positions in the embryo. Read more

Supervisor: Prof C J Weijer

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Molecular characterisation of the factors driving lung fibrosis

University of Dundee School of Life Sciences

Idiopathic pulmonary fibrosis (IPF) is a progressive disease that results in an irreversible decline in lung function. At present IPF is normally fatal and the median survival is between 2 and 5 years after diagnosis. Read more

Supervisors: Prof S Arthur, Dr H McSorley

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Regulation of microglial phenotypes by adenosine and in contribution to ageing in the brain

University of Dundee School of Life Sciences

Microglia are the major innate immune cells in the central nervous system and are required for the response to invading pathogens, removal of damaged or… Read more

Supervisors: Prof S Arthur, Dr A Lloyd

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Mapping the host response to fungal pathogens

University of Dundee School of Life Sciences

Fungal pathogens represent a significant clinical problem for which treatment options remain limited. Read more

Supervisor: Prof S Arthur

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Understanding the beginning of life: the role of non- canonical ubiquitylation in early embryonic development

University of Dundee School of Life Sciences

Ubiquitin is a small, yet influential, protein that is attached to other substrates to control their stability or activity in a process called ubiquitylation. Read more

Supervisor: Dr V De Cesare

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Understanding temperature-dependent virulence regulation in bacterial pathogens

University of Dundee School of Life Sciences

Bacterial pathogens respond rapidly to environmental change, in ways that can influence their growth, virulence, antimicrobial resistance and, therefore, infection outcomes. Read more

Supervisor: Dr D Neill

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Non-canonical functions of SRSF protein kinase (SRPK) in pluripotent stem cells

University of Dundee School of Life Sciences

The overarching goal of our research is to identify and characterise the protein kinase signalling pathways that control stem cell pluripotency and differentiation and determine how protein kinase signalling is disrupted to cause human developmental disorders. Read more

Supervisor: Dr G Findlay

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Targeted protein degradation in plants – developing “Green PROTACs” for functional analysis of lethal genes

University of Dundee School of Life Sciences

Climate change is one of the biggest threats to global food production, leading to unpredictable weather patterns and geographical migration of pathogens. Read more

Supervisor: Dr P Hemsley

Year round applications PhD Research Project Self-Funded PhD Students Only

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