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We have 173 bioinformatics PhD Projects, Programmes & Scholarships

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bioinformatics PhD Projects, Programmes & Scholarships

We have 173 bioinformatics PhD Projects, Programmes & Scholarships

Transcriptome homeostasis in cellular ageing and cancer

Project Summary. We have previously established the oncogenic mechanisms of the transcription factor FOXM1 in perturbation of genome stability (1, 2), epigenome (3, 4) and adult progenitor epithelial stem cell proliferation (5). Read more

Transcriptome biomarkers and mechanisms of chemoresistance

Project Summary. This project aims to identify biomarkers linked to the most potent multimodal anticancer therapy with the least toxicity to counteract hemoresistance in head and neck squamous cell carcinoma (HNSCC). Read more

Identify novel approaches to combat multi drug resistant pathogens

Our research is focused on recalcitrant ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, andEnterobacter species) pathogens; especially hard-to-treat clinical isolates involved in multidrug resistance, biofilm infections and persistence. Read more

Integrated omics approach to psychiatric disorders

  Research Group: Chemistry and Biosciences
In psychiatry, the selection of antipsychotics and antidepressants is led by a trial-and-error approach. The prescribing of these medications is complicated by sub-optimal efficacy and high rates of adverse drug reactions (ADRs). Read more

Revealing low abundant but highly active nitrifiers in coastal sediments

Nitrification is a key global biogeochemical pathway oxidising the most reduced form of nitrogen –ammonia (NH. 3. ), to nitrite (NO) (ammonia oxidation, AO) and then nitrate (nitrite oxidation, NO). Read more

Investigating the innate immune response in RSV and HMPV infection

This is a Self-Funded/Sponsored PhD opportunity. FUNDING REQUIRED. Full UK/EU or International Tuition Fees. UK Living Expenses. Bench Fees (£46,000 total). Read more

AI-based Identification of New Drug Targets for Personalised Oncology

A fully funded PhD Studentship is available to work with Professor Francesca Ciccarelli, Lead of the Centre for Cancer Genomics and Computational Biology, Bart's Cancer Institute at Queen Mary University of London. Read more

Nuclear and transcriptional dysregulations during cellular senescence

Cellular senescence, which is characterised by a proliferation arrest, is a driver of ageing (1). Several stresses can induce cellular senescence, including persistent DNA damage, telomere dysfunction, and oncogene activation. Read more

The Evolution of Vision in Mosquitoes

Background . Due to their capacity to transmit viruses such as Zika and parasites like Plasmodium (the causative agent of malaria), mosquitos are regarded by the World Health Organization as one of the most lethal organisms on our planet (WHO | Global vector control response 2017–2030, 2020). Read more

Identifying the neurogenetic network underlying visually-driven sleep

General background. Sleep is a behavioural quiescence widely observed in the animal kingdom. During sleep, an animal’s motor activity, as well as their responsiveness to environmental stimuli, are largely reduced. Read more

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