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We have 74 differentiation PhD Projects, Programmes & Scholarships

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differentiation PhD Projects, Programmes & Scholarships

We have 74 differentiation PhD Projects, Programmes & Scholarships

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Role of mechanical signals in a 3D human model of alveolar differentiation

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more
 Supervisors: Dr S Loukogeorgakis, Dr F Michielin, Prof P De Coppi
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Stochastic modelling and inference for live-cell gene expression time-series data to unravel the mechanisms of stem cell differentiation

University of St Andrews School of Mathematics and Statistics
  Research Group: Division of Statistics
This project will develop statistical methodology for noisy time-series data and stochastic computational models to analyse live-cell imaging data provided by the lab of our collaborator Dr Cerys Manning at the University of Manchester. Read more
 Supervisor: Dr G Minas
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Self funded MSc by research or PhD in Biology: Membraneless biomelecular condensates, a major regulator of trypanosome parasites differentiation and host adaptation

University of York Department of Biology
Lead supervisor: Dr Mathieu Cayla. Co-Supervisor. Dr Pegine Walrad. The student will be registered with the Department of Biology. Read more
 Supervisor: Dr M Cayla
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Human Genetics, Genomics and Disease: Sequence determinants of mRNA fate in neuronal differentiation

University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: MRC Human Genetics Unit
Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center Berlin Institute for Medical Systems Biology, Berlin, Germany. Read more
 Supervisor: Dr G Kudla
 19 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Duchenne muscular dystrophy (DMD) is a severe X-linked genetic disorder affecting 1:5000 boys at birth (1). DMD is caused by mutations in Dystrophin gene, with around 10% of the cases caused by nonsense mutations (2,3). Read more
 Supervisors: Dr HZ Zhou, Dr J Meng, Prof F Muntoni
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Cell-biological mechanisms mediating primary cilium mediated interpretation of Shh signalling during vertebrate neuronal differentiation

The University of Manchester Faculty of Biology, Medicine and Health
Newborn neurons undergo extensive morphological changes as they polarise to extend axons. In the developing spinal cord, newborn neurons extend axons towards their targets in response to cues from the surrounding tissues. Read more
 Supervisors: Dr R Das, Dr S Herbert
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype

University of Liverpool Institute of Life Course and Medical Sciences
Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more
 Supervisors: Dr R Oldershaw, Dr A Chadwick, Dr M Phelan, Dr BN Norman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Engineering human tissue in vitro: development, characterisation, and application

Durham University Department of Biosciences
Tissues in the human body have a defined structure in that their growth and differentiation have developed in specific ways to create a cellular architecture… Read more
 Supervisor: Prof S Przyborski
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The effect of pharmacotherapy on macrophage differentiation and polarization in cardiometabolic disorders

Charles University Faculty of Pharmacy
Faculty of Pharmacy, Charles University, Department of Pharmacology and Toxicology . Study Program. Pharmacology and Toxicology. Read more
 Supervisor: Prof P Nachtigal
 30 April 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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MSc by Research: Using genome editing to study the mechanisms of immune cell proliferation and differentiation

University of Dundee School of Life Sciences
T lymphocytes mediate long-term adaptive immunity to viruses and tumour cells. T lymphocytes recognize foreign antigens via specific interactions with the T cell receptor (TCR) that is expressed on the cell surface. Read more
 Supervisor: Dr T Ly
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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NIHR Leeds BRC: Pre-clinical evaluation of novel regenerative medicine strategies for knee osteoarthritis

University of Leeds Faculty of Medicine and Health
Historically, articular cartilage was considered incapable of spontaneous repair.  However, biomechanical correction in osteoarthritis (OA) using high tibial osteotomy or joint distraction demonstrated the remarkable joint to regeneration by “merely” correcting joint alignment. Read more
 Supervisors: Prof H Pandit, Prof D McGonagle
 26 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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MSc by Research: Non-canonical functions of SRSF protein kinase (SRPK) in pluripotent stem cells

University of Dundee School of Life Sciences
The overarching goal of our research is to identify and characterise the protein kinase signalling pathways that control stem cell pluripotency and differentiation and determine how protein kinase signalling is disrupted to cause human developmental disorders. Read more
 Supervisor: Dr G Findlay
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role and regulation of membraneless granules for the development of T. brucei

University of York York Biomedical Research Institute
Adaptation to a change of environment is an essential process for survival, in particular for parasitic organisms exposed to a wide range of hosts. Read more
 Supervisors: Dr M Cayla, Dr P B Walrad
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc By Research: Investigating the contextual mechanisms of WNT signalling in hypoblast vs extraembryonic mesoderm specification in early human development using stem cell models

Aberdeen University School of Medicine, Medical Sciences & Nutrition
The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more
 Supervisors: Prof S Hoppler, Dr C Ross
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Using human pluripotent stem cell-based models to study glia-associated biology in neurological diseases

Masaryk University Faculty of Medicine
Affiliation. Masaryk University, Faculty of Medicine. Study program. Ph.D. program Biomedical Sciences. Specialization. Cell and Tissue Morphology. Read more
 Supervisor: Dr DB Bohačiaková
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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