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We have 4 difficile PhD Projects, Programmes & Scholarships

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difficile PhD Projects, Programmes & Scholarships

We have 4 difficile PhD Projects, Programmes & Scholarships

Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more

Identification and characterisation of bacteriocins from environmental samples active against strains of Clostridium difficile.

Clostridiodes difficile is a cause of neonatal enteritis in livestock such as pigs, cattle and horses. Affected animals develop respiratory problems, abdominal distention and bloody diarrhoea leading to weight loss and in extreme cases mortality. Read more

Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile

Clostridioides difficile infection (CDI), the most common cause of infective antibiotic-associated diarrhea in the western world, is diagnosed by a combination of tests that firstly detect the organism, then the toxins that it produces (Planche 2013). Read more

Towards the development of a novel class of broad-spectrum anti-infective drugs

Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more
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