disease PhD Projects, Programmes & Scholarships

We have 750 disease PhD Projects, Programmes & Scholarships

Leveraging novel automated diagnostic pathways with augmented precision medicine approaches for the early detection and risk stratification of liver disease

Liver disease represents one of the fastest-growing causes of morbidity and mortality in the world. The principle aetiological variants are contained within the new nomenclature of steatotic liver disease (SLD). Read more

Supervisors: Dr P Brennan, Prof J F Dillon, Dr M Al-Khairalla

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Selective targeting of furin for the treatment of fibrotic lung disease.

Queen’s University Belfast School of Pharmacy

Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more

Supervisor: Prof L Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identifying variants impacting splicing of 5’ and 3’ UTRs and underpinning inherited retinal disease

The University of Manchester Faculty of Biology, Medicine and Health

Genomic variation that impacts splicing is well established as a cause of genomic disorders, but is almost exclusively limited to protein-coding exons and introns intersecting protein-coding exons. Read more

Supervisors: Dr J Ellingford, Prof R O'Keefe

15 June 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Exploring Parkinson’s disease subtypes using data driven approaches applied to prospective cohorts

University of Bristol Bristol Medical School

Parkinson’s disease is a progressive neurodegenerative disorder characterised by a wide range of motor and non-motor features, for which there is no known cause. Read more

Supervisor: Dr M Lawton

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding the role of adiponectin in kidney disease development at a population level

University of Bristol Bristol Medical School

Reduced circulating adiponectin levels are associated with poor outcome in patients with diabetic kidney disease (DKD) (1). Adiponectin has been shown to be protective against the development of DKD in Type 2 diabetic models (2, 3, 4). Read more

Supervisor: Dr R Foster

Year round applications PhD Research Project Self-Funded PhD Students Only

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Identifying causal risk factors for disease progression

University of Bristol Bristol Medical School

Rationale. Typical epidemiological studies aim to identify causal risk factors for onset of disease by comparing diseased cases with disease free controls. Read more

Supervisors: Dr L Paternoster, Prof G Davey-Smith, Dr A Hartley

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Biomechanical signalling in human heart disease

University of Melbourne Murdoch Childrens Research Institute

About the Project. The human heart undergoes more than 2 billion beats throughout an individual's lifetime, with its rhythm precisely regulated by signalling events that continuously adapt to the biomechanical stress exerted on the ventricular walls. Read more

Supervisor: Dr J McNamara

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Skeletal Muscle Organoid Models for Genetic Mitochondrial Disease (ref: SF22/HLS/APP/Johnson)

Northumbria University Faculty of Health and Life Sciences

Genetic mitochondrial diseases are both clinically and genetically heterogeneous. Read more

Supervisor: Dr S Johnson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical: Gastroesophageal reflux in respiratory disease: pathogenic role and improved management

University of Leeds Faculty of Medicine and Health

Gastroesophageal reflux disease (GERD) is a condition in which stomach contents, such as food and acid pass into the gullet/oesophagus causing heartburn. GERD is very common in patients with lung disease, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). Read more

Supervisors: Prof L Houghton, Dr D Peckham

Year round applications PhD Research Project Self-Funded PhD Students Only

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The Holistic Microbiome in Health and Disease: Linking the Oral, Gut and Respiratory Microbiomes

University of Dundee School of Medicine

The human gut microbiome is recognised as a major determinant of health and disease. Studies to date, including those of the international Human Microbiome Project, have largely focused on individual body sites such as nose or mouth or faeces. Read more

Supervisors: Dr R Hansen, Dr A Dicker, Dr C Mowat

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype

University of Liverpool Institute of Life Course and Medical Sciences

Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more

Supervisors: Dr R Oldershaw, Dr A Chadwick, Dr M Phelan, Dr BN Norman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding the role of mucin genetic variation in lung disease

University of Leicester Department of Genetics and Genome Biology

Research Group: Human & Medical Genetics

Understanding how genetic variation contributes to lung diseases is important in understanding how the disease develops and identifying potential molecular targets for therapy. Read more

Supervisor: Prof E Hollox

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating immune contributions to frontotemporal dementia and motor neuron disease

The University of Manchester Faculty of Biology, Medicine and Health

Frontotemporal dementia (FTD) is the 2nd most common form of dementia affecting younger people, with a typical age of onset in the mid-late 50s. Read more

Supervisors: Dr SR Ryan, Prof D Brough

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cardiovascular growth, function and disease modelling in childhood

University of Melbourne Murdoch Childrens Research Institute

Cardiovascular disease is the leading cause of death globally and there is growing evidence that the precursors of adult heart disease start to form in childhood. Read more

Supervisor: Assoc Prof J Mynard

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Discovery of New Treatments for Parkinson’s disease

Cardiff University Cardiff School of Pharmacy and Pharmaceutical Sciences

Summary. Parkinson’s disease (PD) is the second most common neurological disease in the world. Current PD therapies and medical interventions are very limited and only address the symptoms of this disease highlighting the need for new and effective treatments for this disease. Read more

Supervisor: Dr Y Mehellou

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 750 disease PhD Projects, Programmes & Scholarships

disease PhD Projects, Programmes & Scholarships

We have 750 disease PhD Projects, Programmes & Scholarships

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