in vivo PhD Projects, Programmes & Scholarships

We have 225 in vivo PhD Projects, Programmes & Scholarships

Vascularisation of tumour organoids for mechanistic and drug development

Gliomas such as are the most common form of brain tumour, a subset Glioblastoma (GBM) are devastating adult brain cancer with high rates of recurrence and treatment resistance. Read more

Supervisors: Dr C Murdoch, Dr S Banerjee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigating lysosomal (dys)function in ageing and neurodegeneration

University of Reading Department of Biomedical Sciences

Project Overview. Ageing is associated with a decline in the functions of an organism (López-Otín, C. et al. Cell, 2023) and correlates with an increased risk of developing diseases in the later life (Niccoli, T. Read more

Supervisors: Dr S Cogo, Dr E Kevei

Year round applications PhD Research Project Self-Funded PhD Students Only

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Endosomal Sorting Complex Required for Transport (ESCRT): Investigation of the role in acquired drug resistance in colon cancer

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Despite treatment advances, one of the most common cancers, colorectal cancer (CRC), still has a 45% mortality rate, and one of the major problems is the build-up of resistance to cancer drugs during treatment (‘acquired resistance’) such that over time the drugs stop working. Read more

Supervisors: Dr S Shnyder, Dr S Kantamneni

Year round applications PhD Research Project Self-Funded PhD Students Only

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(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

The University of Manchester Faculty of Biology, Medicine and Health

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

Supervisors: Prof D Brough, Dr K Couper

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Investigating Neuropeptide Signalling From Synthesis to Survival

University of Reading Department of Biomedical Sciences

Neuropeptides, comprising of short amino acid chains, are potent bioactive molecules with extensive neuromodulatory functions and are predominantly expressed within the central nervous system. Read more

Supervisors: Dr A B Bicknell, Dr E Kevei

Year round applications PhD Research Project Self-Funded PhD Students Only

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4-year PhD Studentship: Unlocking the Potential of Sodium Butyrate in Enhancing Chicken Innate Immunity and Poultry Vaccines against Avian Pathogenic Escherichia coli

University of Bristol Bristol Veterinary School

Developing antibiotic alternatives is crucial for managing animal infections and reducing the pressure on antibiotics vital for human medicine. Read more

Supervisor: Prof S Behboudi

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical Gastroenterology: The regulation of GDH expression in Clostridioides difficile

University of Leeds Faculty of Medicine and Health

Clostridioides difficile infection (CDI), the most common cause of infective antibiotic-associated diarrhea in the western world, is diagnosed by a combination of tests that firstly detect the organism, then the toxins that it produces (Planche 2013). Read more

Supervisors: Prof M Wilcox, Dr K Davies, Dr A Buckley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Applying novel imaging methods and machine learning techniques to advance in-vivo knee biomechanics analysis

Cardiff University Cardiff School of Engineering

3 years full time start date July/October 2024. Project Summary. This is an opportunity to work on an exciting project focussed on machine learning applied to in-vivo knee biomechanics working with Cardiff University, Imperial College, Katholieke Universiteit Leuven and University of Florida. Read more

Supervisors: Prof C A Holt, Dr DW Williams

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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How to build and maintain a 3-dimensional polarised epithelial sheet

University of Nottingham School of Life Sciences

We are interested in how cells maintain normal cell shape within an epithelium. Correct epithelial cell shape is essential to maintain tissue integrity and when deregulated can cause diseases such as malignant cancers, diabetes, inflammation, and aging. Read more

Supervisor: Dr M Georgiou

Year round applications PhD Research Project Self-Funded PhD Students Only

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Neurovascular coupling in cerebral hypoperfusion

The University of Manchester Faculty of Biology, Medicine and Health

There are almost a million people living with dementia in the UK. Most of these cases comprise Alzheimer’s Disease (AD), vascular dementia (VaD) or, as is increasingly recognised, a mixed picture phenotype with evidence of the two conditions co-existent in the same patient. Read more

Supervisors: Dr H Pritchard, Dr A Greenstein, Dr I Schiessl, Prof S Allan

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Deciphering the landscape of nucleoporin and lamin function in nucleocytoplasmic communication, nuclear scaffolding and transcriptional control in disease prevention

University of Greenwich School of Pharmacy (Medway Campus)

The nucleus has an instrumental role in cellular responses by coordinating shuttling of components in and out of the nucleus and gene expression with genome architecture and stability. Read more

Supervisors: Dr F Papagiannouli, Dr G Lall

Year round applications PhD Research Project Self-Funded PhD Students Only

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Deciphering the landscape of nucleoporin and lamin function in nucleocytoplasmic communication, nuclear scaffolding and transcriptional control in disease prevention

University of Kent Medway School of Pharmacy

The nucleus has an instrumental role in cellular responses by coordinating shuttling of components in and out of the nucleus and gene expression with genome architecture and stability. Read more

Supervisors: Dr F Papagiannouli, Dr G Lall

Year round applications PhD Research Project Self-Funded PhD Students Only

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Untangling how Shelterin safeguards telomere structure and stability - one molecule at a time

University of Sheffield School of Biosciences

Background. Telomeres solve two problems with linear chromosomes. the end-replication problem, DNA loss from the end of chromosomes every replication cycle; and the end-protection problem, protection of the chromosome ends to prevent chromosome fusions. Read more

Supervisors: Dr M Newton, Dr A Pyne

3 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Duchenne muscular dystrophy (DMD) is a severe X-linked genetic disorder affecting 1:5000 boys at birth (1). DMD is caused by mutations in Dystrophin gene, with around 10% of the cases caused by nonsense mutations (2,3). Read more

Supervisors: Dr HZ Zhou, Dr J Meng, Prof F Muntoni

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Microplastics and Nanoplastics as Emerging Risk Factors in Neurodevelopmental and Neurodegenerative Condition

University of Reading Department of Biomedical Sciences

Project Overview. Microplastics (MPs) and nanoplastics (NPs) are ubiquitous environmental pollutants raising concerns due to their potential adverse effects on human health. Read more

Supervisor: Dr E Kevei

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 225 in vivo PhD Projects, Programmes & Scholarships

in vivo PhD Projects, Programmes & Scholarships

We have 225 in vivo PhD Projects, Programmes & Scholarships

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