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We have 733 life sciences PhD Projects, Programmes & Scholarships

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life sciences PhD Projects, Programmes & Scholarships

We have 733 life sciences PhD Projects, Programmes & Scholarships

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MSc by Research: Resolving immune cell proteomes to subcellular resolution

University of Dundee School of Life Sciences
Immune activation triggers dramatic proteome remodelling. Using high sensitivity mass spectrometry we have mapped immune cell proteomes, providing novel insights into immune cell phenotypes and revealing the metabolic and protein synthesis machinery and environmental sensors that shape cell fate. Read more
 Supervisor: Dr A Howden
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Molecular Analysis of Nuclear Bodies and RNP Trafficking Pathways in the Cell Nucleus

University of Dundee School of Life Sciences
Many important processes within mammalian cells are compartmentalised within specific subcellular structures. In the cell nucleus, Nuclear Bodies (NBs), such as nucleoli, provide specialised compartments that are not surrounded by membranes, but still concentrate specific proteins and RNAs. Read more
 Supervisor: Prof A I Lamond
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Regulation of Kinetochore function by PLK1

University of Dundee School of Life Sciences
Accurate partition of the duplicated genome during cell division is crucial for cellular viability and organismal development. Chromosome mis-segregation is a major source of aneuploidy and it is a hallmark of cancer, while in oocytes represents the major source of miscarriages and genetic disease. Read more
 Supervisor: Dr F G Pelisch
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Deciphering the role(s) of Cdk1 during oocyte meiosis

University of Dundee School of Life Sciences
Meiosis is a specialised type of cell division that produces haploid daughter cells known as gametes that are important for sexual reproduction. Read more
 Supervisor: Dr F G Pelisch
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Investigation of coordination of cell divisions during early embryonic development

University of Dundee School of Life Sciences
Gastrulation is an essential process in early development, during which the forming ectoderm, mesoderm and endoderm take up their correct positions in the embryo. Read more
 Supervisor: Prof C J Weijer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Molecular characterisation of the factors driving lung fibrosis

University of Dundee School of Life Sciences
Idiopathic pulmonary fibrosis (IPF) is a progressive disease that results in an irreversible decline in lung function.  At present IPF is normally fatal and the median survival is between 2 and 5 years after diagnosis. Read more
 Supervisors: Prof S Arthur, Dr H McSorley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Regulation of microglial phenotypes by adenosine and in contribution to ageing in the brain

University of Dundee School of Life Sciences
Microglia are the major innate immune cells in the central nervous system and are required for the response to invading pathogens, removal of damaged or… Read more
 Supervisors: Prof S Arthur, Dr A Lloyd
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Mapping the host response to fungal pathogens

University of Dundee School of Life Sciences
Fungal pathogens represent a significant clinical problem for which treatment options remain limited. Read more
 Supervisor: Prof S Arthur
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Understanding temperature-dependent virulence regulation in bacterial pathogens

University of Dundee School of Life Sciences
Bacterial pathogens respond rapidly to environmental change, in ways that can influence their growth, virulence, antimicrobial resistance and, therefore, infection outcomes. Read more
 Supervisor: Dr D Neill
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Non-canonical functions of SRSF protein kinase (SRPK) in pluripotent stem cells

University of Dundee School of Life Sciences
The overarching goal of our research is to identify and characterise the protein kinase signalling pathways that control stem cell pluripotency and differentiation and determine how protein kinase signalling is disrupted to cause human developmental disorders. Read more
 Supervisor: Dr G Findlay
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Feel the tension – how does S-acylation of OSCA ion channels regulate responses to environmental change in plants?

University of Dundee School of Life Sciences
Plants, being sessile organisms, must sense and respond to environmental change, such as temperature or drought, without being able to move. Read more
 Supervisors: Dr P Hemsley, Prof U Zachariae, Prof M Knight
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: ADP-ribosylation in dementia and motor neuron disease

University of Dundee School of Life Sciences
ADP-ribosylation is a fundamental posttranslational modification where ADP-ribose is linked on to target proteins by ADP-ribose transferases and removed by the ADP-ribose hydrolases. Read more
 Supervisor: Dr L McGurk
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Investigating the tumor suppressor functions of chromatin remodelling

University of Dundee School of Life Sciences
One of the unanticipated outcomes of population based genome sequencing has been the finding that genes involved in the regulation of many genes are mutated at high frequency in tissue specific cancers. Read more
 Supervisor: Prof T A Owen-hughes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Deciphering the ubiquitin codes that regulate protein degradation

University of Dundee School of Life Sciences
Ubiquitin signalling, which involves the posttranslational modification (PTM) of proteins with ubiquitin, regulates almost every aspect of eukaryotic biology. Read more
 Supervisor: Prof Y Kulathu
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Monitoring and manipulating kinase activity in stem cells

University of Dundee School of Life Sciences
Posttranslational modifications of proteins are important regulatory events that impact most if not all physiological functions of cells. Read more
 Supervisor: Dr J Januschke
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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